
%0 Journal Article
%A Clark, BM 
%A Easton, CJ 
%A Watkins, SK 
%T Copper Catalyzed Reactions of Penicillin Derivatives With t-Butyl Perbenzoate
%J Australian Journal of Chemistry
%D 1995/05/01
%V 48
%N 5
%P 1065-1070
%K 
%R https://doi.org/10.1071/CH9951065
%U https://www.publish.csiro.au/paper/CH9951065 
%X The benzoyloxylation of penicillin derivatives at C5, on treatment with t-butyl perbenzoate in the presence of a copper catalyst, is facilitated by a phthalimido group at C6 when the substituents on the lactam ring are in the cis orientation, but hindered when the groups are trans substituted. In the absence of a C6 substituent, a competing reaction occurs in which the thiazolidine ring is cleaved. 
