
TY  - JOUR
A1  - Clark, BM 
A1  - Easton, CJ 
A1  - Watkins, SK 
T1  - Copper Catalyzed Reactions of Penicillin Derivatives With t-Butyl Perbenzoate
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1995
VL  - 48
IS  - 5
SP  - 1065
EP  - 1070
KW  - 
UR  - https://doi.org/10.1071/CH9951065 
N2  - The benzoyloxylation of penicillin derivatives at C5, on treatment with t-butyl perbenzoate in the presence of a copper catalyst, is facilitated by a phthalimido group at C6 when the substituents on the lactam ring are in the cis orientation, but hindered when the groups are trans substituted. In the absence of a C6 substituent, a competing reaction occurs in which the thiazolidine ring is cleaved. 
ER  -

