
TY  - JOUR
A1  - Badran, TW 
A1  - Chai, CLL 
A1  - Easton, CJ 
A1  - Harper, JB 
A1  - Page, DM 
T1  - Directing Bromination of Piperazine-2,5-diones
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1995
VL  - 48
IS  - 7
SP  - 1379
EP  - 1384
KW  - 
UR  - https://doi.org/10.1071/CH9951379 
N2  - From intermolecular and intramolecular competition experiments, it has been established that, by comparison with an N-methyl substituent, an N-acetyl group deactivates glycine residues in piperazine-2,5-diones towards free-radical bromination. Combined with the ease of introduction and removal of N-acetyl substituents, the deactivating effect provides a method for regiocontrolled functionalization of these compounds. 
ER  -

