
%0 Journal Article
%A Guard, JAM 
%A Steel, PJ 
%T Heterocyclic Tautomerism. IX. Structural Revision of a Series of Pharmacologically Active Pyridazines
%J Australian Journal of Chemistry
%D 1995/09/01
%V 48
%N 9
%P 1601-1607
%K 
%R https://doi.org/10.1071/CH9951601
%U https://www.publish.csiro.au/paper/CH9951601 
%X On the basis of 1H n.m.r. n.O.e. Measurements and an X-ray crystal structure determination, it is shown that a large series of pharmacologically active pyridazine derivatives should be represented as aromatic pyridazine tautomers [e.g. (1b)-(3b)], rather than the previously reported arylidene-4,5-dihydropyridazines [e.g. (1a)-(3a)]. Crystals of (7b) are monoclinic, P21/c, a 13.312(3), b 7.269(1), c 11.753(2) &#506;, &#946; 101.38(3)&#176;, Z = 4; the structure was refined to a conventional R[I > 2&#963;(I)] 0.037. 
