
TY  - JOUR
A1  - Guard, JAM 
A1  - Steel, PJ 
T1  - Heterocyclic Tautomerism. IX. Structural Revision of a Series of Pharmacologically Active Pyridazines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1995
VL  - 48
IS  - 9
SP  - 1601
EP  - 1607
KW  - 
UR  - https://doi.org/10.1071/CH9951601 
N2  - On the basis of 1H n.m.r. n.O.e. Measurements and an X-ray crystal structure determination, it is shown that a large series of pharmacologically active pyridazine derivatives should be represented as aromatic pyridazine tautomers [e.g. (1b)-(3b)], rather than the previously reported arylidene-4,5-dihydropyridazines [e.g. (1a)-(3a)]. Crystals of (7b) are monoclinic, P21/c, a 13.312(3), b 7.269(1), c 11.753(2) &#506;, &#946; 101.38(3)&#176;, Z = 4; the structure was refined to a conventional R[I > 2&#963;(I)] 0.037. 
ER  -

