
TY  - JOUR
A1  - Tilley, RI 
A1  - Leslie, DR 
T1  - Rates of Reaction of the Sulfoxides and Sulfones of Sulfur Mustard and 2-Chloroethyl Ethyl Sulfide With Hydroxide Ion in Water
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1995
VL  - 48
IS  - 10
SP  - 1781
EP  - 1786
KW  - 
UR  - https://doi.org/10.1071/CH9951781 
N2  - The reactions of the sulfoxides and sulfones of sulfur mustard and an analogue, 2-chloroethyl ethyl sulfide, with hydroxide ion in aqueous solution at 25&#176; have been studied. In contrast with the behaviour of the parent sulfides, for which exclusive substitution of chlorine is observed under comparable conditions, the oxidized compounds react through base-catalysed elimination of HCl to give the corresponding alkenes. Second-order rate constants for these reactions are reported and implications for the metabolism of sulfur mustard are discussed. 
ER  -

