
%0 Journal Article
%A Waugh, RJ 
%A Steinborner, ST 
%A Bowie, JH 
%A Wallace, JC 
%A Tyler, MJ 
%A Hu, PF 
%A Gross, ML 
%T Two Isomeric &#945; and &#946; Aspartyl Dodecapeptides and Their Cyclic Amino Succinyl Analogue From the Australian Green Tree Frog <I>Litoria gilleni</I>
%J Australian Journal of Chemistry
%D 1995/12/01
%V 48
%N 12
%P 1981-1987
%K 
%R https://doi.org/10.1071/CH9951981
%U https://www.publish.csiro.au/paper/CH9951981 
%X Three related peptides, caeridins 1.1-1.3, have been isolated from the green tree frog Litoria gilleni. Caeridins 1.1 and 1.2 are dodecapeptides differing only in having &#945; and &#946; Asp at residue 4 [viz. Gly Leu Leu Asp Gly Leu Leu Gly Thr Leu Gly Leu (NH2)]. Caeridin 1.3 is the corresponding cyclic amino succinyl derivative derived formally by cyclization of Asp(4) and Gly (5). Hydrolysis of caeridin 1.3 yields caeridin 1.1 and 1.2 in the ratio 3:1. This constitutes a rare case of the isolation of three such related peptides from a natural system. 
