
TY  - JOUR
A1  - Matyus, P 
A1  - Barlin, GB 
A1  - Harrison, PW 
A1  - Wong, MG 
A1  - Davies, LP 
T1  - Ligands for the Central Benzodiazepine Receptor: Structure&#8211;Affinity Relationship Studies on Imidazo[1,2-b]pyridazines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1996
VL  - 49
IS  - 4
SP  - 435
EP  - 442
KW  - 
UR  - https://doi.org/10.1071/CH9960435 
N2  - Seventy-six imidazo [1,2-b] pyridazines and some bicyclic isomers have been analysed and compared in terms of geometric and electronic requirements for binding to central benzodiazepine receptors. The binding sites identified for these compounds by molecular modelling are consistent with known benzodiazepine receptor- ligand interaction models. However, for the most active compounds, additional binding sites are proposed. 
ER  -

