
TY  - JOUR
A1  - Hambley, TW 
A1  - Hambley, TW 
A1  - Lewis, KG 
A1  - Lewis, KG 
A1  - Tucker, DJ 
A1  - Tucker, DJ 
A1  - Turner, P 
A1  - Turner, P 
T1  - Properties of Olean-12-ene-3&#945;,16&#946;,22&#945;,28-tetrol and Some Derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1996
VL  - 49
IS  - 7
SP  - 775
EP  - 783
KW  - 
UR  - https://doi.org/10.1071/CH9960775 
N2  - Reaction of olean-12-ene-3&#946;,16&#946;,22&#945;,28-tetrol ( chichipegenin ) (1) with methyl orthoformate gives the 16&#946;,22&#945;,28-orthoformate (2). Acetylation of the ortho ester followed by hydrolysis gives the tetrol 3&#946;-monoacetate (5). It is shown that intramolecular hydrogen bonding occurs in the tetrol (1) and the 3&#946;-monoacetate (5) in non-polar solvents. X-Ray crystallographic data on the tetrol and its tetraacetate (4) are reported. The tetrol,C30H50O4, M 474.72, crystallized in the orthorhombic space group P 212121 with a 12.363(6), b 31.888(3), c 6.962(3) &#506;, V 2745(1) &#506;3, Dc(Z = 4) 1.149 g cm-3, N = N(unique) 2394, No 1878 [I > 1.5&#963;(I)], Nvar 500; R 0.038, Rw 0.040. The tetraacetate , C38H58O8, M 642.87, crystallized in the monoclinic space group P 21, with a 10.603(2), b 16.569(1), c 10.814(1) &#506;, &#946; 98.72(1)&#176;, V 1877.9(4) &#506;3, Dc(Z = 2) 1.137g cm-3 N 3090, Rmerge 4.67% for N(unique) 2917, No 2663 [I > 2.5&#963;(I)], Nvar 414; R 0.053, Rw 0.050. 
ER  -

