
%0 Journal Article
%A Lawrence, RM 
%A Perlmutter, P 
%T The Synthesis and Some Manipulations of Dialkyl 6-Aryl (or Alkyl)-2-oxotetrahydro-2H-pyran-3,5-dicarboxylates
%J Australian Journal of Chemistry
%D 1996/08/01
%V 49
%N 8
%P 839-845
%K 
%R https://doi.org/10.1071/CH9960839
%U https://www.publish.csiro.au/paper/CH9960839 
%X A new, one-pot annulation process, involving conjugate addition of the sodium salts of dimethyl (or dibenzyl ) malonate to alkyl 2-(1- hydroxyalkyl ) propenoates, produces a mixture of dialkyl 6-aryl(or alkyl)-2-oxotetrahydro-2H-pyran-3,5-dicarboxylates. Alkylations of the cis-isomers were found to be highly stereoselective . The ntroduction of unsaturation into these molecules is also described. 
