
TY  - JOUR
A1  - Lawrence, RM 
A1  - Perlmutter, P 
T1  - The Synthesis and Some Manipulations of Dialkyl 6-Aryl (or Alkyl)-2-oxotetrahydro-2H-pyran-3,5-dicarboxylates
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1996
VL  - 49
IS  - 8
SP  - 839
EP  - 845
KW  - 
UR  - https://doi.org/10.1071/CH9960839 
N2  - A new, one-pot annulation process, involving conjugate addition of the sodium salts of dimethyl (or dibenzyl ) malonate to alkyl 2-(1- hydroxyalkyl ) propenoates, produces a mixture of dialkyl 6-aryl(or alkyl)-2-oxotetrahydro-2H-pyran-3,5-dicarboxylates. Alkylations of the cis-isomers were found to be highly stereoselective . The ntroduction of unsaturation into these molecules is also described. 
ER  -

