
%0 Journal Article
%A Mata, G 
%A Masters, DG 
%A Buscall, D 
%A Street, K 
%A Schlink, AC 
%T Responses in wool growth, liveweight, glutathione and amino acids, in Merino wethers fed increasing amounts of methionine protected from degradation in the rumen
%J Australian Journal of Agricultural Research
%D 1995/09/01
%V 46
%N 6
%P 1189-1204
%K methionine;rumen-protected methionine;wool;liveweight;glutathione;sulfur
%R https://doi.org/10.1071/AR9951189
%U https://www.publish.csiro.au/paper/AR9951189 
%X The aim of the experiments reported was to evaluate the protection from microbial breakdown of two methionine formulations (Lactet and Mepron) and to measure responses in wool production, liveweight, amino acids and glutathione in blood and tissues when one of these forms of methionine (Lactet) was supplied to merino wethers fed at maintenance. Lactet was well protected against microbial breakdown in the rumen. Peak values for concentrations of methionine in plasma, following administration of the different forms of methionine into the rumen, were 574, 148 and 143pmol L-1 for Lactet, DL-methionine and Mepron. Production responses to dosed levels of Lactet (0, 1, 2, 3, 5, 8 g methionine dayw1) were measured over 63 days in the animal house. Significant linear responses were obtained for wool growth (4-38%), fibre diameter (0.5-2 8m) and liveweight gain (30-1 15%). Concentrations of reduced glutathione in blood, liver and skin were increased, at some times during the experiment, by provision of Lactet. However, responses were inconsistent and highly variable among sheep, Glutathione was of limited use as an indicator of sulfur amino acid intake or status. Sulfate in plasma increased markedly at all levels of Lactet intake, and there was a linear relationship between Lactet intake and the concentration of sulfur in wool. Plasma free methionine and the ratio of methionine to total essential amino acids showed significant linear responses to the supplements. It was concluded that Lactet was an effective method of supplying rumen-protected methionine to ruminants. 
