
%0 Journal Article
%A Dilani Senadheera, M 
%A M Lévesque, Céline 
%A G Cvitkovitch, Dennis 
%T Signal peptide pheromones in oral streptococcal biofilms
%J Microbiology Australia
%D 2005/09/01
%V 26
%N 3
%P 124-126
%K 
%R https://doi.org/10.1071/MA05124
%U https://www.publish.csiro.au/paper/MA05124 
%X Oral streptococci are known to modulate various physiological properties by responding to secreted signal peptide pheromones. These molecules accumulate in the environment and trigger a genetic response in the target cells at a threshold cell density, thereby synchronising a metabolic outcome with population density. In this review, we summarise how signal peptide pheromones of oral streptococci function. The possibility of targeting these peptide pheromones for the prevention of biofilm-associated infections such as dental caries is also discussed. 
