
TY  - JOUR
A1  - Mortimer, MR 
A1  - Connell, DW 
T1  - Bioconcentration factors and kinetics of chlorobenzenes in a juvenile crab (<I>Portunus pelagicus</I> (L))
JF  - Marine and Freshwater Research
JO  - Mar. Freshwater Res.
Y1  - 1993
VL  - 44
IS  - 4
SP  - 565
EP  - 576
KW  - 
UR  - https://doi.org/10.1071/MF9930565 
N2  - The uptake- and depuration-rate constants (k1 and k2 respectively), according to first-order kinetics,  were measured for a series of chlorobenzenes with juvenile crabs, Portunus pelagicus. These constants  were found to be related to the lipophilicity of the chlorobenzenes as expressed by the octanol-water  coefficient (log Kow), giving relationships similar to those observed with fish. However, the actual  magnitude of k1 and k2 on a lipid basis ranged from 720 to 5880 h-1 and from 0.492 to 0.0102 h-1 respectively, which is about ten times faster than those for fish. The bioconcentration factor (KB in wet  weight units) obtained from these rate constants was related to Kow, by the following expression. log KB=-2.88+1.09 log Kow.   The empirical constants in this equation are similar to those observed with other aquatic organisms  except that the value of -2.88 is lower than that reported with the other organisms. This is probably  due to the relatively low lipid content of the crabs. It is suggested that the bioconcentration of essentially  nonbiodegradable lipophilic compounds occurs as a result of partitioning between biota lipid and water.  Other physicochemical properties (molar volume and aqueous solubility) and two molecular descriptors  (zero- and first-order Randik indices) exhibited good correlations with the bioconcentration characteristics  described above. 
ER  -

