
TY  - JOUR
A1  - Meldrum, DR 
A1  - Marr, B 
A1  - Stubbs, C 
A1  - Wisot, A 
A1  - Yeo, l 
A1  - Hamilton, F 
T1  - Impaired Uterine Receptivity
in Infertile Women over Age 40
having Oocyte Donation and Correction
with Increased Progesterone Replacement
JF  - Reproduction, Fertility and Development
JO  - Reprod. Fertil. Dev.
Y1  - 1992
VL  - 4
IS  - 6
SP  - 689
EP  - 693
KW  - 
UR  - https://doi.org/10.1071/RD9920689 
N2  - Significantly fewer ongoing and delivered pregnancies occurred in infertile women aged >40 years receiving oocyte donation from young normal women (8%, P<0.02) than in a similar group of younger recipients receiving identical treatment (43%). A significant improvement (46Yo ongoing and delivered, P<0.01) was achieved in another group of women over 40, treated with a doubled dose of progesterone. The results are consistent with those observed in animal studies and suggest an effect of ageing on uterine receptivity that is at least partly correctable by augmented progesterone stimulation of the endometrium. 
ER  -

