
%0 Journal Article
%A Liang, ZG 
%A O'Hern, PA 
%A Yavetz, B 
%A Yavetz, H 
%A Goldberg, E 
%T Human testis cDNAs identified by sera from infertile patients: a molecular biological approach to immunocontraceptive development
%J Reproduction, Fertility and Development
%D 1994/06/01
%V 6
%N 3
%P 297-305
%K 
%R https://doi.org/10.1071/RD9940297
%U https://www.publish.csiro.au/paper/RD9940297 
%X Sera from patients with known or suspected immunological infertility were used to screen a human testis cDNA library. A total of 59 sera detected 38 unique cDNA inserts of which four were testis specific by Northern blot analyses. One of these is a testis-specific isoform of calpastatin. Five additional clones, although not testis specific, were found to be testis abundant. The number and type of clones identified by these human sera suggests a possible aetiology for immunologic infertility. The testis-specific clones will be further characterized to establish their usefulness as contraceptive vaccine candidates. 
