
TY  - JOUR
A1  - Liang, ZG 
A1  - O'Hern, PA 
A1  - Yavetz, B 
A1  - Yavetz, H 
A1  - Goldberg, E 
T1  - Human testis cDNAs identified by sera from infertile patients: a molecular biological approach to immunocontraceptive development
JF  - Reproduction, Fertility and Development
JO  - Reprod. Fertil. Dev.
Y1  - 1994
VL  - 6
IS  - 3
SP  - 297
EP  - 305
KW  - 
UR  - https://doi.org/10.1071/RD9940297 
N2  - Sera from patients with known or suspected immunological infertility were used to screen a human testis cDNA library. A total of 59 sera detected 38 unique cDNA inserts of which four were testis specific by Northern blot analyses. One of these is a testis-specific isoform of calpastatin. Five additional clones, although not testis specific, were found to be testis abundant. The number and type of clones identified by these human sera suggests a possible aetiology for immunologic infertility. The testis-specific clones will be further characterized to establish their usefulness as contraceptive vaccine candidates. 
ER  -

