
%0 Journal Article
%A Bradley, MP 
%T Experimental strategies for the development of an immunocontraceptive vaccine for the European red fox, Vulpes vulpes
%J Reproduction, Fertility and Development
%D 1994/06/01
%V 6
%N 3
%P 307-317
%K 
%R https://doi.org/10.1071/RD9940307
%U https://www.publish.csiro.au/paper/RD9940307 
%X The development of an immunocontraceptive vaccine to control fox populations in Australia would confer considerable advantages in controlling the long-term impact of this predator on native and endangered species. Studies are currently under way to identify sperm antigens that might be used in such a vaccine, and some of these studies are described. It is proposed that such a vaccine would be delivered orally in a bait, thereby stimulating a mucosal immune response to the foreign antigen(s). Such a vaccine requires a detailed understanding of reproductive-tract mucosal immunity in foxes, and selection of the most effective form of antigen delivery. Those under consideration include viral or bacterial vectors and microencapsulated antigens. 
