
%0 Journal Article
%A Koopman, P 
%T The molecular biology of SRY and its role in sex determination in mammals
%J Reproduction, Fertility and Development
%D 1995/08/01
%V 7
%N 4
%P 713-722
%K 
%R https://doi.org/10.1071/RD9950713
%U https://www.publish.csiro.au/paper/RD9950713 
%X SRY is the gene that initiates the genetic cascade leading to testis development in mammals. Since its discovery in 1990 and the direct demonstration of its male-determining role in transgenic mice, attention has turned to understanding the biochemical mode of action of the SRY gene product, and to the identification of other genes in the sex-determining pathway. Recent progress in these efforts is summarized in this review. 
