
%0 Journal Article
%A Jones, AR 
%A Porter, LM 
%T Inhibition of glycolysis in boar spermatozoa by alpha-chlorohydrin phosphate appears to be mediated by phosphatase activity
%J Reproduction, Fertility and Development
%D 1995/10/01
%V 7
%N 5
%P 1089-1094
%K 
%R https://doi.org/10.1071/RD9951089
%U https://www.publish.csiro.au/paper/RD9951089 
%X (R,S)-alpha-chlorohydrin-1-phosphate, previously shown to have no anti-glycolytic activity on mature boar sperm in vitro, is a substrate for acid and/or neutral phosphatase(s) that are associated with washed sperm. The high phosphatase activity hydrolyses the ester to alpha-chlorohydrin which undergoes oxidation to (S)-3-chlorolactaldehyde, a specific inhibitor of sperm glyceraldehyde-3-phosphate dehydrogenase and triosephosphate isomerase, thereby exhibiting an anti-glycolytic action. 
