Some Effects of Fluoride on Calcium Metabolism in the Bones of Young Rats

Abstract

Radioautography has indicated that in rats which were fed fluoride in the food at a rate of 400 p.p.m. (as sodium fluoride), and then injected with 17·6 JLc 45Ca, a process occurred which tended to cause a wider distribution of 45Ca activity throughout the epiphyseal and trabecular regions of the femora and humeri. It also appeared that the labelled calcium was retained in these regions to a greater extent than in the control animals.