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RESEARCH ARTICLE

Hydatid disease - still a global problem

Marshall Lightowlers A C and David Jenkins B
+ Author Affiliations
- Author Affiliations

A University of Melbourne, Veterinary Clinical Centre, 250 Princes Highway, Werribee, Victoria 3030, Australia;

B Charles Sturt University, Wagga School of Animal and Veterinary Sciences, Locked Bag 588, Wagga Wagga, NSW 2678 Australia

C Tel 03 9731 2284
Fax 03 9731 2366
Email marshall@unimelb.edu.au

Microbiology Australia 33(4) 157-159 https://doi.org/10.1071/MA12157
Published: 1 November 2012

Abstract

Hydatid disease (cystic echinococcosis) remains highly prevalent and a serious cause of human morbidity and mortality in many parts of the world. While there are some regions where the disease has been controlled, most efforts to control transmission of the parasite have had limited success. Recent genetic data indicates that Echinococcus granulosus, which was formally thought to be a single species, comprises a number of distinct species. The vast majority of human infections are caused by the most common genotype which is generally transmitted by sheep and goats. Renewed hope for effective control of the parasite’s transmission has followed the development of the EG95 vaccine that can be used to reduce infection levels in livestock animals thereby reducing the reliance of control measures on interventions in dogs.


References

[1]  Jenkins, D. J. (2006) Echinococcus granulosus in Australia, widespread and doing well! Parasitol. Int. 55, S203–206.
Echinococcus granulosus in Australia, widespread and doing well!Crossref | GoogleScholarGoogle Scholar |

[2]  Jenkins, D. J. (2005) Hydatid control in Australia: where it began, what we have achieved and where to from here. Int. J. Parasitol. 35, 733–740.
Hydatid control in Australia: where it began, what we have achieved and where to from here.Crossref | GoogleScholarGoogle Scholar |

[3]  Larrieu, E. et al.. (2004) Ultrasonographic diagnosis and medical treatment of human cystic echinococcosis in asymptomatic school age carriers: 5 years of follow-up. Acta Trop. 91, 5–13.
Ultrasonographic diagnosis and medical treatment of human cystic echinococcosis in asymptomatic school age carriers: 5 years of follow-up.Crossref | GoogleScholarGoogle Scholar |

[4]  P. R. Torgerson, P. Craig, (2011) 2. Updated global burder of cystic and alveolar echinococcosis. In: Report of the WHO Informal Working Group on cystic and alveolar echinococcosis surveillance, prevention and control, with the participation of the Food and Agriculture Organization of the United Nations and the World Organisation for Animal Health, 22–23 June 2011, Department of Control of Neglected Tropical Diseases, WHO, Geneva, Switzerland, ISBN 978 92 4 150292 4, p. 1.

[5]  Jenkins, D. J. et al.. (2005) Emergence/re-emergence of Echinococcus spp.--a global update. Int. J. Parasitol. 35, 1205–1219.
Emergence/re-emergence of Echinococcus spp.--a global update.Crossref | GoogleScholarGoogle Scholar |

[6]  Nakao, M. et al.. (2010) State-of-the-art Echinococcus and Taenia: phylogenetic taxonomy of human-pathogenic tapeworms and its application to molecular diagnosis. Infect. Genet. Evol. 10, 444–452.
State-of-the-art Echinococcus and Taenia: phylogenetic taxonomy of human-pathogenic tapeworms and its application to molecular diagnosis.Crossref | GoogleScholarGoogle Scholar |

[7]  Krabbe, H. (1864) Athugasemdir handa Íslendingum um sullaveikina og varnir móti henni, Kaupmannah[UNKNOWN ENTITY &odie;]fn Prentað hjá J.H. Schultz.

[8]  Pharo, H. (2002) Decades of hydatids control work pays off. Biosecurity 38, 7.

[9]  M. J. Middleton, (2001) Provisional freedom. In Eradication in our lifetime. A log book of the tasmanian Hydatid Control Programs 1962-1996 (Beard, T.C. et al., eds), pp. 347-351, Department of Primary Industry, Water and Environment.

[10]  PAHO (2002) Perspectives and possibilities of control and eradication of hydatidosis. Report of the PAHO/WHO Working Group, San Carlos de Bariloche, 20-24 September 1999, Argentina. PAHO/HCP/HCV/028/02, Pan American Health Organization.

[11]  Craig, P. S. and Larrieu, E. (2006) Control of cystic echinococcosis/hydatidosis: 1863-2002. Adv. Parasitol. 61, 443–508.
Control of cystic echinococcosis/hydatidosis: 1863-2002.Crossref | GoogleScholarGoogle Scholar |

[12]  K. Polydorou, (1995) Echinococcosis/hydatidosis eradication in Cyprus. In Proceedings of the Scientific Working Group on the Advances in the Prevention, Control and Treatment of Hydatidosis. 26-28 October 1994, Montevideo, Uruguay (Ruiz, A. et al., eds), pp. 113-122, Pan American Health Organization PAHO/HCP/HCV/95/01.

[13]  Lightowlers, M. W. et al.. (1996) Vaccination against hydatidosis using a defined recombinant antigen. Parasite Immunol. 18, 457–462.
Vaccination against hydatidosis using a defined recombinant antigen.Crossref | GoogleScholarGoogle Scholar |

[14]  Lightowlers, M. W. et al.. (1999) Vaccination trials in Australia and Argentina confirm the effectiveness of the EG95 hydatid vaccine in sheep. Int. J. Parasitol. 29, 531–534.
Vaccination trials in Australia and Argentina confirm the effectiveness of the EG95 hydatid vaccine in sheep.Crossref | GoogleScholarGoogle Scholar |

[15]  Heath, D. D. et al.. (2003) Progress in control of hydatidosis using vaccination-a review of formulation and delivery of the vaccine and recommendations for practical use in control programmes. Acta Trop. 85, 133–143.
Progress in control of hydatidosis using vaccination-a review of formulation and delivery of the vaccine and recommendations for practical use in control programmes.Crossref | GoogleScholarGoogle Scholar |

[16]  Torgerson, P. R. and Heath, D. D. (2003) Transmission dynamics and control options for Echinococcus granulosus. Parasitology 127, S143–158.
Transmission dynamics and control options for Echinococcus granulosus.Crossref | GoogleScholarGoogle Scholar |

[17]  Barnes, T. S. et al.. (2009) Efficacy of the EG95 hydatid vaccine in a macropodid host, the tammar wallaby. Parasitology 136, 461–468.
Efficacy of the EG95 hydatid vaccine in a macropodid host, the tammar wallaby.Crossref | GoogleScholarGoogle Scholar |

[18]  Romig, T. et al.. (2007) Impact of praziquantel baiting on intestinal helminths of foxes in southwestern Germany. Helminthologia 44, 206–213.
Impact of praziquantel baiting on intestinal helminths of foxes in southwestern Germany.Crossref | GoogleScholarGoogle Scholar |