Register      Login
Australian Health Review Australian Health Review Society
Journal of the Australian Healthcare & Hospitals Association
RESEARCH ARTICLE

Provision of home medicines reviews in Australia: linking population need with service provision and available pharmacist workforce

Jean Spinks A B H , Stephen Birch C , Amanda J. Wheeler B , Lisa Nissen D , Christopher Freeman E F , Thao Thai G and Joshua Byrnes A B
+ Author Affiliations
- Author Affiliations

A Centre for Applied Health Economics, Griffith University, N78, 1.11, Nathan Campus, 170 Kessels Road, Nathan, Qld 4111, Australia. Email: j.byrnes@griffith.edu.au

B Menzies Health Institute Queensland, Griffith University, Brisbane, Qld 4111, Australia. Email: a.wheeler@griffith.edu.au

C Centre for the Business and Economics of Health, University of Queensland, Brisbane, Qld 4072, Australia. Email: stephen.birch@uq.edu.au

D Faculty of Health, Queensland University of Technology, Brisbane, Qld 4000, Australia. Email: l.nissen@qut.edu.au

E School of Pharmacy, University of Queensland, Brisbane, Qld 4072, Australia. Email: c.freeman4@uq.edu.au

F Pharmaceutical Society of Australia (PSA), Deakin, ACT 2600, Australia.

G Centre for Health Economics, Monash University, Caulfield, Melbourne, Vic. 3162, Australia. Email: thao.t.thai@monash.edu

H Corresponding author. Email: j.spinks@griffith.edu.au

Australian Health Review 44(6) 973-982 https://doi.org/10.1071/AH19207
Submitted: 9 October 2019  Accepted: 7 February 2020   Published: 20 November 2020

Abstract

Objective Identifying and quantifying the health needs of a population are the basis of evidence-based health policy and workforce planning. The motivation for undertaking the present study was to evaluate whether the current level of medication review services corresponds to population need, as proxied by the rate of polypharmacy, and to undertake a preliminary analysis of the sufficiency of the current workforce. This paper: (1) estimates the age- and sex-standardised rates of polypharmacy as a proxy for population need for home medicines review; (2) compares the rate of polypharmacy with current service provision of home medicines reviews; and (3) links the estimated need for services with the current number and location of pharmacist providers.

Methods Age- and sex-adjusted polypharmacy rates, by state, were estimated from the National Health Survey of Australia (2017–18), service levels were estimated from national-level administrative claims data (2017–18) and the current workforce was estimated from the Australian Association of Consultant Pharmacists (2018). The current level of service provision was compared to the estimated population need for services, alongside the size of the pharmacy workforce required if need was met.

Results The adjusted rate of polypharmacy in Australia, using the strictest definition of ≥10 medications and ≥3 current chronic illnesses, was 1389 per 100 000 population. The illustrative needs-based analysis suggests that there may be a disconnect between the current level of service provision and population health needs.

Conclusion Given that polypharmacy is a risk factor for medication-related problems, and that medication review is one of the few targeted strategies currently available to address medication-related problems in the population, service provision may be inadequate. Policy options to improve service provision could include interventions to increase workforce productivity and relaxing the current eligibility criteria for review, especially in rural and remote areas.

What is known about the topic? Polypharmacy is a risk factor for medication-related problems, which can cause increased morbidity and mortality in the population.

What does this paper add? This paper provides representative, population-based rates of polypharmacy in Australia and uses these rates in a needs-based analysis of service provision and workforce adequacy to provide home medicines review services.

What are the implications for practitioners? Several policy options are available for consideration, including interventions to increase workforce productivity and relaxation of the current eligibility criteria for medicines review, especially in rural and remote areas.


References

[1]  Birch S, Kephart G, Tomblin-Murphy G, O’Brien-Pallas L, Alder R, MacKenzie A. Human resources planning and the production of health: a needs-based analytical framework. Can Public Policy 2007; 33 S1–16.
Human resources planning and the production of health: a needs-based analytical framework.Crossref | GoogleScholarGoogle Scholar |

[2]  Birch S, Mason T, Sutton M, Whittaker W. Not enough doctors or not enough needs? Refocusing health workforce planning from providers and services to populations and needs. J Health Serv Res Policy 2013; 18 107–13.
Not enough doctors or not enough needs? Refocusing health workforce planning from providers and services to populations and needs.Crossref | GoogleScholarGoogle Scholar |

[3]  Masnoon N, Shakib S, Kalisch-Ellett L, Caughey GE. What is polypharmacy? A systematic review of definitions. BMC Geriatr 2017; 17 230
What is polypharmacy? A systematic review of definitions.Crossref | GoogleScholarGoogle Scholar | 29017448PubMed |

[4]  Cooper JA, Cadogan CA, Patterson SM, Kerse N, Bradley MC, Ryan C, Hughes CM. Interventions to improve the appropriate use of polypharmacy in older people: a Cochrane systematic review. BMJ Open 2015; 5 e009235
Interventions to improve the appropriate use of polypharmacy in older people: a Cochrane systematic review.Crossref | GoogleScholarGoogle Scholar | 26656020PubMed |

[5]  Steinman MA. Polypharmacy – time to get beyond numbers. JAMA Intern Med 2016; 176 482–3.
| 26999383PubMed |

[6]  Patterson SM, Cadogan CA, Kerse N, Cardwell CR, Bradley MC, Ryan C, Hughes CM. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev 2014; 9 CD008165

[7]  Qato DM, Wilder J, Schumm P, Gillet V, Alexander C. Changes in prescription and over-the-counter medication and dietary supplement use among older adults in the United States, 2005 vs 2011. JAMA Intern Med 2016; 176 473–82.
| 26998708PubMed |

[8]  Nobili A, Pasina L, Tettamanti M, Lucca U, Riva E, Marzona I, Monesi L, Cucchiani R, Bortolotti A, Fortino I, Merlino L, Walter Locatelli G, Giuliani G. Potentially severe drug interactions in elderly outpatients: results of an observational study of an administrative prescription database. J Clin Pharm Ther 2009; 34 377–86.
Potentially severe drug interactions in elderly outpatients: results of an observational study of an administrative prescription database.Crossref | GoogleScholarGoogle Scholar | 19583670PubMed |

[9]  Viktil KK, Blix HS, Moger TA, Reikvam A. Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems. Br J Clin Pharmacol 2007; 63 187–95.
Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems.Crossref | GoogleScholarGoogle Scholar | 16939529PubMed |

[10]  Pharmaceutical Care Network Europe (PCNE). PCNE classification for drug related problems V9.00. Zuidlaren: PCNE; 2019. Available at: https://www.pcne.org/upload/files/334_PCNE_classification_V9-0.pdf [verified 24 August 2020].

[11]  Aparasu RR, Mort JR. Inappropriate prescribing for the elderly: Beers criteria-based review. Ann Pharmacother 2000; 34 338–46.
Inappropriate prescribing for the elderly: Beers criteria-based review.Crossref | GoogleScholarGoogle Scholar | 10917382PubMed |

[12]  Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003; 163 2716–24.
Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts.Crossref | GoogleScholarGoogle Scholar | 14662625PubMed |

[13]  O’Mahony D, Gallagher P, Ryan C, Byrne S, Hamilton H, Barry P, O’Connor M, Kennedy J. STOPP & START criteria: a new approach to detecting potentially inappropriate prescribing in old age. Eur Geriatr Med 2010; 1 45–51.
STOPP & START criteria: a new approach to detecting potentially inappropriate prescribing in old age.Crossref | GoogleScholarGoogle Scholar |

[14]  O’Mahony D, O’Sullivan D, Byrne S, O’Connor MN, Ryan C, Gallagher P. STOPP/START criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing 2015; 44 213–18.
STOPP/START criteria for potentially inappropriate prescribing in older people: version 2.Crossref | GoogleScholarGoogle Scholar | 25324330PubMed |

[15]  Williams M, Peterson GM, Tenni PC, Bindoff IK, Stafford AC. DOCUMENT: a system for classifying drug-related problems in community pharmacy. Int J Clin Pharm 2012; 34 43–52.
DOCUMENT: a system for classifying drug-related problems in community pharmacy.Crossref | GoogleScholarGoogle Scholar | 22101425PubMed |

[16]  Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, Farra K, Park KB, Breckenridge AM. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ 2004; 329 15–19.
Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients.Crossref | GoogleScholarGoogle Scholar | 15231615PubMed |

[17]  Donaldson LJ, Kelley ET, Dhingra-Kumar N, Kieny M-P, Sheikh A. Medication without harm: who’s third global patient safety challenge. Lancet 2017; 389 1680–1.
Medication without harm: who’s third global patient safety challenge.Crossref | GoogleScholarGoogle Scholar | 28463129PubMed |

[18]  Aitken M, Gorokhovich L. Advancing the responsible use of medicines: applying levers for change. Parsippany, NJ: IMS Institute for Healthcare Informatics; 2012.

[19]  Pharmaceutical Society of Australia (PSA). Medication safety: take care. Canberra: PSA; 2019. Available at: https://www.psa.org.au/wp-content/uploads/2019/01/PSA-Medicine-Safety-Report.pdf [verified 19 September 2019].

[20]  Australian Government Department of Health (DoH). MBS online. Canberra: DoH; 2019. Available at: http://www.mbsonline.gov.au/internet/mbsonline/publishing.nsf/Content/Home [verified 5 September 2019].

[21]  Pharmacy Programs Administrator (PPA). Program rules: home medicines review. Melbourne: PPA; 2020. Available at: https://www.ppaonline.com.au/wp-content/uploads/2019/01/HMR-Program-Rules.pdf [verified 5 September 2019].

[22]  Du W, Gnjidic D, Pearson S-A, Hilmer SN, McLachlan AJ, Blyth F, Viney R, Joshy G, Day K, Banks E. Patterns of high-risk prescribing and other factors in relation to receipt of a home medicines review: a prospective cohort investigation among adults aged 45 years and over in Australia. BMJ Open 2019; 9 e027305
Patterns of high-risk prescribing and other factors in relation to receipt of a home medicines review: a prospective cohort investigation among adults aged 45 years and over in Australia.Crossref | GoogleScholarGoogle Scholar | 30975675PubMed |

[23]  Australian Government Department of Health (DoH). Medication use review (MedsCheck) and diabetes medication management services (Diabetes MedsCheck). Canberra: DoH; 2014. Available at: https://www1.health.gov.au/internet/main/publishing.nsf/Content/fifth-community-pharmacy-agreement-mur [verified 5 September 2019].

[24]  Williams M, Peterson GM, Tenni PC, Bindoff IK, Curtain C, Hughes J, Bereznicki LR, Jackson S, Kong D, Hughes JD. Drug-related problems detected in Australian community pharmacies: the PROMISe trial. Ann Pharmacother 2011; 45 1067–76.
Drug-related problems detected in Australian community pharmacies: the PROMISe trial.Crossref | GoogleScholarGoogle Scholar | 21878658PubMed |

[25]  Kalisch LM, Caughey GE, Barratt JD, Ramsay EN, Killer G, Gilbert AL, Roughead E. Prevalence of preventable medication-related hospitalizations in Australia: an opportunity to reduce harm. Int J Qual Health Care 2012; 24 239–49.
Prevalence of preventable medication-related hospitalizations in Australia: an opportunity to reduce harm.Crossref | GoogleScholarGoogle Scholar | 22495574PubMed |

[26]  Roughhead L, Semple S, Rosenfeld E. Literature review: medication safety in Australia. Sydney: Australian Commission on Safety and Quality in Health Care; 2013. Available at: https://www.safetyandquality.gov.au/sites/default/files/migrated/Literature-Review-Medication-Safety-in-Australia-2013.pdf [verified 16 December 2019].

[27]  Pharmacy Guild of Australia, Australian Government Department of Health (DoH). FAQ – ensuring sustainability and delivering efficiencies. Canberra: DoH, Pharmacy Guild of Australia; 2014. Available at: http://6cpa.com.au/wp-content/uploads/FAQ-Ensuring-sustainability-and-delivering-efficiencies-11-Mar-20141.pdf [verified 9 September 2019].

[28]  White L, Klinner C, Carter S. Consumer perspectives of the Australian home medicines review program: benefits and barriers. Res Social Adm Pharm 2012; 8 4–16.
Consumer perspectives of the Australian home medicines review program: benefits and barriers.Crossref | GoogleScholarGoogle Scholar | 21493164PubMed |

[29]  Swain LS, Barclay L. Exploration of Aboriginal and Torres Strait Islander perspectives of home medicines review. Rural Remote Health 2015; 15 3009
| 25711405PubMed |

[30]  Wheeler AJ, Spinks J, Kelly F, Ware RS, Vowles E, Stephens M, Scuffham P, Miller A. Protocol for a feasibility study of an Indigenous Medication Review Service (IMeRSe) in Australia. BMJ Open 2018; 8 e026462
Protocol for a feasibility study of an Indigenous Medication Review Service (IMeRSe) in Australia.Crossref | GoogleScholarGoogle Scholar | 30391923PubMed |

[31]  Australian Bureau of Statistics (ABS). National health survey: first results 2017–18. Canberra: ABS; 2018. Available at: https://www.abs.gov.au/ausstats/abs@.nsf/mf/4364.0.55.001 [verified 15 September 2019].

[32]  Duerden M, Avery T, Payne R. Polypharmacy and medicines optimisation. Making it safe and sound. London: The King’s Fund; 2013. Available at: https://www.kingsfund.org.uk/sites/default/files/field/field_publication_file/polypharmacy-and-medicines-optimisation-kingsfund-nov13.pdf [verified 16 December 2019].

[33]  Johnston MC, Crilly M, Black C, Prescott GJ, Mercer SW. Defining and measuring multimorbidity: a systematic review of systematic reviews. Eur J Public Health 2019; 29 182–9.
Defining and measuring multimorbidity: a systematic review of systematic reviews.Crossref | GoogleScholarGoogle Scholar | 29878097PubMed |

[34]  Stata Statistical Software. dstize – direct and indirect standardisation. Stata Statistical Software, Release 13. College Station, TX: StataCorp LP; n.d. Available at: https://www.stata.com/manuals13/rdstdize.pdf [verified 9 September 2019].

[35]  Pharmacy Programs Administrator (PPA). Indexation of service payments. Melbourne: PPA; 2019. Available at: https://www.ppaonline.com.au/indexation-2019-20 [verified 27 August 2019].

[36]  Hugo Centre for Migration and Population Research. Pharmacy Access/Remoteness Index of Australia (PhARIA). Adelaide: University of Adelaide; 2018. Available at: https://www.adelaide.edu.au/hugo-centre/services/pharia [verified 5 September 2019].

[37]  Bennett A, Johnsen S, Smith C, Hurst R, Chen T. A comparative study of two collaborative models for the provision of domiciliary medication review. Sydney: Faculty of Pharmacy, University of Sydney and St George Division of General Practice; 2000.

[38]  Australian Institute of Health and Welfare (AIHW). The health and welfare of Australia’s Aboriginal and Torres Strait Islander peoples: 2015. Canberra: AIHW; 2015. Available at: https://www.aihw.gov.au/reports/indigenous-health-welfare/indigenous-health-welfare-2015/contents/table-of-contents [verified 5 September 2019].

[39]  Pharmaceutical Society of Australia (PSA). Guidelines for pharmacists providing MedsCheck and Diabetes MedsCheck services. Canberra: PSA; 2017. Available at: https://www.ppaonline.com.au/wp-content/uploads/2019/01/PSA-MedsCheck-Guidelines.pdf [verified 9 September 2019].

[40]  Holland R, Desborough J, Goodyer L, Hall S, Wright D, Loke YK. Does pharmacist-led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta-analysis. Br J Clin Pharmacol 2008; 65 303–16.
Does pharmacist-led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta-analysis.Crossref | GoogleScholarGoogle Scholar | 18093253PubMed |

[41]  Ryan R, Santesso N, Lowe D, Hill S, Grimshaw JM, Prictor M, Kaufman C, Cowie G, Taylor M. Interventions to improve safe and effective medicines use by consumers: an overview of systematic reviews. Cochrane Database Syst Rev 2014; 4 CD007768
Interventions to improve safe and effective medicines use by consumers: an overview of systematic reviews.Crossref | GoogleScholarGoogle Scholar |