The Evolution of Non-Additive Genetic Variance Under Artificial Selection I. Modification of Dominance At a Single Autosomal Locus

Abstract

The papers to be published in this series are concerned with the behaviour under directional selection of genetic systems showing non-allelic interaction. The aim is to describe in quantitative terms the conditions under which overdorninance may evolve under the usual conditions of laboratory experimentation, and to examine the stability of the resultant populations. In this first paper, a general method of approach to problems of the modification of dominance is outlined, and the necessary theory developed.