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EDITORIAL

Getting pre-exposure prophylaxis (PrEP) to the people: opportunities, challenges and examples of successful health service models of PrEP implementation

Iryna B. Zablotska A F , Jared M. Baeten B , Nittaya Phanuphak C , Sheena McCormack D and Jason Ong E
+ Author Affiliations
- Author Affiliations

A Faculty of Medicine and Health, The University of Sydney, 162 Marsden Street, Parramatta, NSW 2150, Australia.

B Schools of Medicine and Public Health, University of Washington, 325 Ninth Ave, Box 359927, Seattle, WA 98104, USA.

C The Thai Red Cross AIDS Research Centre, Bangkok, 104 Rajdumri Road, Pathumwan, Bangkok 10330, Thailand.

D MRC Clinical Trials Unit at UCL, University College London, 90 High Holborn, London WC1V 6LJ, UK.

E London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

F Corresponding author. Email: iryna.zablotska@sydney.edu.au

Sexual Health 15(6) 481-484 https://doi.org/10.1071/SH18182
Submitted: 25 September 2018  Accepted: 4 October 2018   Published: 29 November 2018

Abstract

Pre-exposure prophylaxis (PrEP) with antiretrovirals could prevent millions of infections, yet effective strategies to get PrEP delivered are just being defined. This editorial introduces a series of 17 articles which form a special issue of Sexual Health focused on the opportunities and challenges for health service providers engaged in PrEP prescribing. All pieces presented here share useful lessons from PrEP pioneers; more than that, they should serve as catalysts to accelerate PrEP implementation around the world.


References

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[11]  Davies N, Heffron R. Global and national guidance for the use of pre-exposure prophylaxis during peri-conception, pregnancy and breastfeeding. Sex Health 2018; 15 501–512.

[12]  Reyniers T, Vuylsteke B, Pirotte B, Hoornenborg E, Bil JP, Wouters K, Laga M, Nöstlinger C. Physicians’ preparedness for pre-exposure prophylaxis: results of an online survey in Belgium. Sex Health 2018; 15 606–611.

[13]  Wood BR, Mann MS, Martinez-Paz N, Unruh KT, Annese M, Spach DH, Scott JD, Stekler JD. Project ECHO: telementoring to educate and support prescribing of HIV pre-exposure prophylaxis by community medical providers. Sex Health 2018; 15 601–605.

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[15]  Girometti N, McCormack S, Devitt E, Gedela K, Nwokolo N, Patel S, Suchak T, McOwan A, Whitlock G. Evolution of a pre-exposure prophylaxis (PrEP) service in a community-located sexual health clinic: concise report of the PrEPxpress. Sex Health 2018; 15 598–600.

[16]  Schmidt H-MA, McIver R, Houghton R, Selvey C, McNulty A, Varma R, Grulich AE, Holden J. Nurse-led pre-exposure prophylaxis: a non-traditional model to provide HIV prevention in a resource-constrained, pragmatic clinical trial. Sex Health 2018; 15 595–597.

[17]  Tung EL, Thomas A, Eichner A, Shalit P. Implementation of a community pharmacy-based pre-exposure prophylaxis service: a novel model for pre-exposure prophylaxis care. Sex Health 2018; 15 556–561.

[18]  Phanuphak N, Sungsing T, Jantarapakde J, Pengnonyang S, Trachunthong D, Mingkwanrungruang P, Sirisakyot W, Phiayura P, Seekaew P, Panpet P, Meekrua P, Praweprai N, Suwan F, Sangtong S, Brutrat P, Wongsri T, Rattakittvijun Na Nakorn P, Mills S, Avery M, Vannakit R, Phanuphak P. Princess PrEP program: the first key population-led model to deliver pre-exposure prophylaxis to key populations by key populations in Thailand. Sex Health 2018; 15 542–555.

[19]  Schwartz K, Ferrigno B, Vining S, Gomez A, Briedenhann E, Gardiner E, Jeckonia P, Torjesen K. PrEP Communications Accelerator: a digital demand creation tool for sub-Saharan Africa. Sex Health 2018; 15 570–577.

[20]  Sharpe JD, Kamara MT. A systematic evalution of mobile apps to improve the update of and adherence to HIV pre-exposure prophylaxis. Sex Health 2018; 15 587–594.

[21]  Sullivan PS, Siegler AJ. Getting pre-exposure prophylaxis (PrEP) to the people: opportunities, challenges and emerging models of PrEP implementation. Sex Health 2018; 15 522–527.

[22]  Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, Tappero JW, Bukusi EA, Cohen CR, Katabira E, Ronald A, Tumwesigye E, Were E, Fife KH, Kiarie J, Farquhar C, John-Stewart G, Kakia A, Odoyo J, Mucunguzi A, et al Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med 2012; 367 399–410.
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[23]  Masyuko S, Mukui I, Njathi O, Kimani M, Oluoch P, Wamicwe J, Mutegi J, Njogo S, Anyona M, Muchiri P, Maikweki L, Musyoki H, Bahati P, Kyongo J, Marwa T, Irungu E, Kiragu M, Kioko U, Ogando J, Were D, et al Pre-exposure prophylaxis rollout in a national public sector program: the Kenyan case study. Sex Health 2018; 15 578–586.

[24]  Hood JE, Eljallad T, Abad J, Connolly M, Heumann C, Fritz J, Roach M, Lukomski D, Golden MR. Getting pre-exposure prophylaxis to high-risk transgender women: lessons from Detroit, USA. Sex Health 2018; 15 562–569.

[25]  Tan RKJ, Teo AKJ, Kaur N, Harrison-Quintana J, I-Cheng Chen M, Wong CS. Cost and anonymity as factors for the effective implementation of pre-exposure prophylaxis: an observational study among gay, bisexual and other men who have sex with men in Singapore. Sex Health 2018; 15 533–541.

[26]  Dunbar MS, Kripke K, Haberer J, Castor D, Dalal S, Mukoma W, Mullick S, Patel P, Reed J, Subedar H, Were D, Warren M, Torjesen K. Understanding and measuring uptake and coverage of oral pre-exposure prophylaxis delivery among adolescent girls and young women in sub-Saharan Africa. Sex Health 2018; 15 513–521.