Conditions Affecting the Action of Fluoroacetate on The Metabolism of Nematode Parasites and Vertebrate Animals

Abstract

The respiration of brei or mince prepared from pigeon breast muscle containing 0.0003M methylene blue was very little affected by O.OIM Huoroacetate. Under similar conditions, the respiration of preparations from Ascaridia galli and Nematodirus spp. was inhibited 3.5-50 per cent. This inhibition was lessened by adding intermediates of the tricarboxylic acid cycle. Succinate was most effective in lifting the inhibition; oxaloacetate was least effective.