Evidence-based practice?

Abstract

In 1948, the world of health and medical research changed forever with the publication of the Medical Research Council?s randomised controlled trial (RCT) on the use of streptomycin in the treatment of tuberculosis (TB).1,2 In that year, there were 341 papers on Streptomycin and TB published in the medical literature, but only one RCT, and this was the paper that defined a generation of TB treatment. The process of undertaking RCTs was quickly developed to include health promotion.