CSIRO Publishing Books Journals About Us Shopping Cart You are here: Journals > Wildlife Research   
Wildlife Research
  Ecology, Management and Conservation in Natural and Modified Habitats
 
Search
 
 
  Advanced Search
   

Journal Home
About the Journal
Editorial Board
Contacts
Content
Online Early
Current Issue
Just Accepted
All Issues
Special Issues
Sample Issue
For Authors
General Information
Notice to Authors
Submit Article
Open Access
For Referees
General Information
Review Article
Annual Referee Index
For Subscribers
Subscription Prices
Customer Service
Print Publication Dates

 Early Alert
Subscribe to our email Early Alert or RSS feeds for the latest journal papers.

 Connect with us
facebook   youtube

 CSIRO Wildlife Research
All volumes of CSIRO Wildlife Research are online and available to subscribers of Wildlife Research.

 

Article << Previous     |     Next >>   Contents Vol 34(1)

Oral toxicity of p-aminopropiophenone to ferrets

P. Fisher A, C. O’Connor B

A Landcare Research, PO Box 40, Lincoln 7640, New Zealand.
B Biosecurity New Zealand, Animal Welfare Group, PO Box 2526, Wellington, New Zealand.
 
PDF (107 KB) $25
 Export Citation
 Print
  


Abstract

Ferrets (Mustela furo) are pests in New Zealand and new methods are being sought for their control. The hydrochloride form of p-aminopropiophenone (PAPP) was highly toxic to ferrets when delivered by gavage, with LD50 and LD99 values of 15.52 and 20.80 mg kg–1, respectively. Signs of toxicosis progressed through pallor and cyanosis, impaired coordination, prostration with reduced responses to stimuli, with death in ~2 h. In a preliminary assessment of effective doses of PAPP in bait, 19 of 20 ferrets consumed chick carcasses containing ~46 mg PAPP within 40 min. Ferrets that ate chick baits all showed signs of toxicosis, with 32% mortality. Three ferrets died within 151 min and the other three within the following 14 h. Ferrets that died ingested 29.9–79.3 mg PAPP per kilogram bodyweight. The low mortality was attributed to decreased bioavailability of PAPP delivered in food, and increased doses need to be tested to establish an effective lethal concentration of PAPP in baits for ferrets. Future development of bait formulations will also need to take into account the role of emesis in reducing efficacy. Bait formulations incorporating microencapsulated PAPP may improve bioavailability and the basis for a new option for the management of ferrets in New Zealand.

   
Subscriber Login
Username:
Password:  

    


 
Top  Email this page
 
Legal & Privacy | Contact Us | Help

CSIRO

© CSIRO 1996-2012