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RESEARCH ARTICLE

Bacterial vaginosis in female sex workers in Chennai, India

Shanmugasundaram Uma A , Pachamuthu Balakrishnan A E , Kailapuri G. Murugavel A , Aylur K. Srikrishnan A , Nagalingeswaran Kumarasamy A , Jebaraj A. Cecelia A , Santhanam Anand A , Kenneth H. Mayer B , David Celentano C , Sadras P. Thyagarajan D and Suniti Solomon A

A YRG Center for AIDS Research and Education, VHS, Taramani, Chennai-600113, India.

B Department of Medicine, Brown University/Miriam Hospital, Providence, RI, USA.

C Department of Epidemiology, John’s Hopkins University School of Public Health, Baltimore, USA.

D Department of Microbiology, Dr.A.L.M. PGIBMS, University of Madras, Taramani, Chennai-600113, India.

E Corresponding author. Email: bala@yrgcare.org

Sexual Health 2(4) 261-262 http://dx.doi.org/10.1071/SH05025
Submitted: 4 May 2005  Accepted: 23 September 2005   Published: 16 November 2005

Abstract

Bacterial vaginosis (BV) causes obstetric and gynaecological complications and non-chlamydial/non-gonococcal pelvic inflammatory disease and has been shown to be associated with the risk of acquiring HIV and herpes simplex (HSV)-2 infections. This study investigated both the prevalence of BV and its association with STDs among 582 female sex workers living in Chennai, South India. Blood, vaginal and endocervical swabs were tested for HSV-2, HIV, Treponema pallidum, BV, Chlamydia trachomatis, Neisseria gonorrhoea and Trichomonas vaginalis. The vaginal swabs collected were Gram’s stained and analysed for BV by Nugent’s scoring criteria. Of the women studied, 45% (95% CI, 40.6–48.7) were positive, 39.5% (95% CI, 35.5–43.5) were negative and 16% (95% CI, 12.8–18.7) were intermediate for BV. Bacterial vaginosis positivity was directly related to concurrent infection with HSV-2 (RR 1.3, AR 12, P = 0.00), T. vaginalis (RR 1.5, AR 10, P = 0.01) T. pallidum (RR 2.8, AR 16, P = 0.00) and HIV (RR 4.1, AR 52, P = 0.01). Future studies are needed to focus on the risk factors for BV.


References

[1]  Centers for Diseases Control and Prevention 1998 Guidelines for treatment of sexually transmitted diseases. Morb Mortal Wkly Rep 47 70 4

[2]  Centers for Disease Control and Prevention 2002 Sexually transmitted diseases treatment guidelines 2002. Morb Mortal Wkly Rep 51 42 4


[3]  Morris M Nicoll A Simms I Wilson J Catchpole M 2001 Bacterial vaginosis; a public health review. Br J Obstet Gynecol 108 439 50
DOI

[4]  Koumans EH Kendrick JS 2001 Preventing adverse sequelae of bacterial vaginosis: a public health program and research agenda. Sex Transm Dis 28 292 7 DOI Pubmed Abstract

[5]  Cherpes TL Meyn LA Krohn MA Lurie JG Hillier SL 2003 Association between acquisition of herpes simplex virus type 2 in women and bacterial vaginosis. Clin Infect Dis 37 319 25 DOI Pubmed Abstract

[6]  Sewankambo N Gray RH Wawer MJ Paxton L McNaim D Wabwire-Mangen F et al 1997 HIV infection associated with abnormal vaginal flora morphology and bacterial vaginosis. Lancet 350 546 50 DOI Pubmed Abstract

[7]  Schimd GP 1999 The epidemiology of bacterial vaginosis. Int J Gynecol 67 17 20 DOI

[8]  Cohen CR Duerr A Pruithithada N Rugpao S Hillier S Garcia P et al 1995 Bacterial vaginosis and HIV seroprevalence among female commercial sex workers in Chiang Mai, Thailand. AIDS 9 1093 7 Pubmed Abstract

[9]  Nugent RP Krohn MA Hillier SL 1991 Reliability of diagnosing Bacterial vaginosis is improved by a standardized method of Gram stain interpretation. J Clin Microbiol 29 297 301 Pubmed Abstract

[10]  Moi H 1990 Prevalence of Bacterial vaginosis and its association with genital infections, inflammation, and contraceptive methods in women attending sexually transmitted disease and primary health clinics. Int J STD AIDS 1 86 94 Pubmed Abstract

[11]  Schmidt H Hansen JG 2000 Bacterial vaginosis in a family practice population. Acta Obstet Gynecol Scand 79 999 1005 DOI Pubmed Abstract

[12]  Watcharotone W Sirimai K Kiriwat O Nukoolkarn P Watcharaprapapong O Pibilmanee S et al 2004 Prevalence of Bacterial vaginosis in Thai women attending the family planning clinic, Siriraj Hospital. J Med Assoc Thai 87 1419 24 Pubmed Abstract

[13]  Amsel R Totten PA Spiegel CA Chen KCS Eschenbach D Holmes KK 1983 Nonspecific vaginosis. Diagnostic criteria and microbial and epidemiological associations. Am J Med 74 14 22 DOI Pubmed Abstract

[14]  Morris MC Rogers PA Kinghorn GR 2001 Is bacterial vaginosis a sexually transmitted infection? Sex Transm Inf 77 63 8 DOI



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