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Sexual Health Sexual Health Society
Publishing on sexual health from the widest perspective

Pending research issues in male condom use promotion

Richard Crosby A B D and Lee Warner C

A College of Public Health, University of Kentucky, 121 Washington Avenue, Lexington, KY 40506, USA.

B Rural Center for AIDS/STD Prevention, Indiana University, 801 East 7th Street, Bloomington, IN 47405, USA.

C Centers for Disease Control and Prevention, Division of Reproductive Health, Atlanta, GA 30341, USA.

D Corresponding author. Email:

Sexual Health 5(4) 317-319
Submitted: 28 October 2008  Accepted: 30 October 2008   Published: 18 November 2008


Sufficient evidence has accumulated to warrant the expansion of condom use research in several additional directions. Possible risk compensation pertaining to human papillomavirus vaccination and vaginal microbicides is one example. A second area of needed research involves the question of when couples can be advised to safely discontinue condom use given that ‘lifelong’ condom use is not a realistic goal for most people. A third example is intensified research designed to identify more effective means of mass marketing condoms and their use as a health-protective behaviour. As the AIDS and sexually transmissible infection pandemics persist, intensified condom promotion research is an ethical imperative.

Additional keywords: condom effectiveness, condom failure, sexual behaviour, sexually transmissible infections.


[1]  National Institute of Allergies and Infectious Disease. Workshop Summary: scientific evidence on condom effectiveness for sexually transmitted disease (STD) prevention. Bethesda, MD: National Institute of Allergies and Infectious Disease; 2001.

[2]  Holmes KK Levine R Weaver M 2004 Effectiveness of condoms in preventing sexually transmitted infections. Bull World Health Organ 82 454 61

[3]  Warner L Stone KM Macaluso M Buehler J Austin HD 2006 Condom use and risk of gonorrhea and chlamydia: a systematic review of design and measurement factors assessed in epidemiologic studies. Sex Transm Dis 33 36 51

[4]  Weller S Davis-Beaty K 2001 Condom effectiveness in reducing heterosexual HIV transmission. Cochrane Database Syst Rev 1 CD003255

[5]  Warner L Macaluso M Austin HD Kleinbaum DK Artz L Fleenor ME et al 2005 Application of the case-crossover design to reduce unmeasured confounding in studies of condom effectiveness. Am J Epidemiol 161 765 73

[6]  Warner L Newman DR Austin HD Kamb ML Douglas JM Jr Malotte CK et al 2004 Condom effectiveness for reducing transmission of gonorrhea and chlamydia: the importance of assessing partner infection status. Am J Epidemiol 159 242 51 doi:10.1093/aje/kwh044

[7]  Winer RL Hughes JP Feng Q O’Reilly S Kiviat NB Holmes KK et al 2006 Condom use and the risk of genital human papillomavirus infection in young women. N Engl J Med 354 2645 54 doi:10.1056/NEJMoa053284

[8]  Hogewoning CJA Bleeker MCG van den Brule AJC Voorhorst FJ Snijders PJF Berkhof J et al 2003 Condom use promotes regression of cervical intraepithelial neoplasia and clearance of human papillomavirus: a randomized controlled trial. Int J Cancer 107 811 16 doi:10.1002/ijc.11474

[9]  Crosby RA Salazar LF DiClemente RJ Yarber WL Caliendo AM Staples-Horne M 2005 Accounting for failures may improve precision: evidence supporting improved validity of self-reported condom use. Sex Transm Dis 32 513 15 doi:10.1097/01.olq.0000170442.10150.28

[10]  Crosby RA Sanders S Yarber WL Graham C Dodge B 2002 Condom use errors and problems among college men. Sex Transm Dis 29 552 7 doi:10.1097/00007435-200209000-00010

[11]  Crosby RA Sanders SA Yarber WL Graham CA 2003 Condom use errors and problems: a neglected aspect of studies assessing condom effectiveness. Am J Prev Med 24 367 70 doi:10.1016/S0749-3797(03)00015-1

[12]  Civic D Scholes D Ichikawa L Grothaus L McBride CM Yarnall KSH 2002 Ineffective use of condoms among young women in managed care. AIDS Care 14 779 88 doi:10.1080/0954012021000031859

[13]  Macaluso M Kelaghan J Artz L Austin H Fleenor M Hook EW et al 1999 Mechanical failure of the latex condom in a cohort of women at high STD risk. Sex Transm Dis 26 450 7 doi:10.1097/00007435-199909000-00006

[14]  Warner L Clay-Warner J Boles J Williamson J 1998 Assessing condom use practices: implications for evaluating method and user effectiveness. Sex Transm Dis 6 273 7

[15]  Shlay JC McClung MW Patnaik JL Douglas JM 2004 Comparison of sexually transmitted disease prevalence by reported condom use: errors among consistent condom users seen at an urban sexually transmitted disease clinic. Sex Transm Dis 31 526 32

[16]  Macaluso M Blackwell R Jamieson DJ Kulczycki A Chen MP Akers R et al 2007 Efficacy of the male latex condom and of the female polyurethane condom as barriers to semen during intercourse: a randomized clinical trial. Am J Epidemiol 166 88 96 doi:10.1093/aje/kwm046

[17]  Koutsky L Ault KA Wheeler CM Brown DR Barr E Alvarez FB et al 2002 A controlled trial of a human papillomavirus type 16 vaccine. N Engl J Med 347 1645 51 doi:10.1056/NEJMoa020586

[18]  Munoz N Bosch FX de Sanjose S Herrero R Castellsagué X Shah KV et al 2003 Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med 348 518 27 doi:10.1056/NEJMoa021641

[19]  van de Wijgert J Coggins C 2002 Microbicides to prevent heterosexual transmission of HIV: ten years down the road. AIDScience 15 23 8

[20]  Mantell JE Myer L Carballo-Dieguez A Steina Z Ramjee G Morar NS et al 2005 Microbicide acceptability research: current approaches and future directions. Soc Sci Med 60 319 30

[21]  Ramjee G Shattock R Delany S McGowan I Morar N Gottemoeller M 2006 Microbicides 2006 conference. AIDS Res Ther 3 25 doi:10.1186/1742-6405-3-25

[22]  Kajubi P Kamya MR Kamya S Chen S McFarland W Hearst N 2005 Increasing condom use without reducing HIV risk: results of a controlled community trial in Uganda. J Acquir Immune Defic Syndr 40 77 82 doi:10.1097/01.qai.0000157391.63127.b2

[23]  Smoak ND Scott-Sheldon LA Johnson BT Carey MP 2006 Sexual risk reduction interventions do not inadvertently increase the overall frequency of sexual behavior: a meta-analysis of 174 studies with 116,735 participants. J Acquir Immune Defic Syndr 41 374 84 doi:10.1097/01.qai.0000185575.36591.fc

[24]  Centers for Disease Control and Prevention 2002 Sexually transmitted diseases treatment guidelines 2002. MMWR Morb Mortal Wkly Rep 51 1 60 RR-6

[25]  Crosby RA DiClemente RJ Holtgrave DR Wingood GM 2002 Design, measurement, and analytic considerations for testing hypotheses relative to condom effectiveness against non-viral STIs. Sex Transm Infect 78 228 31

[26]  Crosby RA Graham CA Yarber WL Sanders SA 2004 If the condom fits, wear it: a qualitative study of young African American men. Sex Transm Infect 80 306 9 doi:10.1136/sti.2003.008227

[27]  Crosby RA Yarber WL Sanders SA Graham CA 2005 Condom discomfort and associated problems with their use among university students. J Am College Health 54 143 8 doi:10.3200/JACH.54.3.143-148

[28]  Crosby RA Yarber WL Sanders SA Graham CA McBride K Milhausen RR et al 2007 Men with broken condoms: who and why? Sex Transm Infect 83 71 5 doi:10.1136/sti.2006.021154

[29]  Cook L Nanda K Taylor D 2001 Randomized crossover trial comparing the eZ.on plastic condom and a latex condom. Contraception 63 25 31 doi:10.1016/S0010-7824(00)00193-1

[30]  Trussell J Warner DL Hatcher RA 1992 Condom breakage and slippage rates. Fam Plann Perspect 24 20 3 doi:10.2307/2135721

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