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RESEARCH ARTICLE

A case of apparent resistance to all available antiretroviral drugs in a HIV-positive patient

Doris Chibo A C , Norman Roth B and Chris Birch A
+ Author Affiliations
- Author Affiliations

A Victorian Infectious Diseases Reference Laboratory, 10 Wreckyn Street, North Melbourne, Vic. 3051, Australia.

B Prahran Market Clinic, 131 Commercial Road, South Yarra, Vic. 3141, Australia.

C Corresponding author. Email: doris.chibo@mh.org.au

Sexual Health 7(1) 82-84 https://doi.org/10.1071/SH09032
Submitted: 16 March 2009  Accepted: 24 November 2009   Published: 15 February 2010

Abstract

We describe a case of multidrug and class resistant HIV in a patient with psychological issues affecting his adherence. The complexities involved in subsequent treatment decisions when resistance interpretation algorithms are discordant are discussed.

Additional keywords: adherence factors, interpretive algorithms, multi-drug resistance, raltegravir resistance.


Acknowledgements

We thank the Signe Fransen and scientists at Monogram Biosciences for their help with performing the PhenoSense GT assay and for advice and intellectual input on the assay performance. The method for VIDRL’S in-house integrase genotyping assay is available on request.


References


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