Register      Login
Sexual Health Sexual Health Society
Publishing on sexual health from the widest perspective
RESEARCH ARTICLE (Open Access)

Cost and anonymity as factors for the effective implementation of pre-exposure prophylaxis: an observational study among gay, bisexual and other men who have sex with men in Singapore

Rayner Kay Jin Tan A D , Alvin Kuo Jing Teo A , Nashwinder Kaur B , Jack Harrison-Quintana C , Mark I-Cheng Chen A B and Chen Seong Wong B
+ Author Affiliations
- Author Affiliations

A Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, #10-01, 117549 Singapore.

B National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, 308442 Singapore.

C Grindr for Equality, 750 N San Vicente Blvd, West Hollywood, CA 90069, USA.

D Corresponding author. Email: e0145771@u.nus.edu

Sexual Health 15(6) 533-541 https://doi.org/10.1071/SH18059
Submitted: 2018 March 30  Accepted: 2018 May 26   Published: 25 September 2018

Journal Compilation © CSIRO 2018 Open Access CC BY-NC-ND

Abstract

Background: HIV pre-exposure prophylaxis (PrEP) is currently offered by several public and private clinics at unsubsidised prices in Singapore, but to date, no information is available on the effect of these services. This study sought to assess the knowledge and uptake of, and willingness to use PrEP among gay, bisexual and other men who have sex with men (GBMSM) in Singapore. Methods: Recruitment was conducted through Grindr®, a geosocial networking application for GBMSM. Results were quantitatively analysed through descriptive statistics and multivariate Poisson regression models, while open-ended responses were qualitatively coded and categorised. Results: Of the 1339 participants who responded, 1098 participants who indicated their knowledge and use of PrEP were included in the analytic sample. Overall, 15.0% (n = 154) had taken PrEP, 66.2% (n = 678) had heard of but not taken PrEP, while 18.8% (n = 193) had never heard of PrEP. Of those who had ever taken PrEP, 59.6% (n = 90) had obtained PrEP from overseas or other unofficial sources. Of those who had heard of but never taken PrEP, 73.3% (n = 486) reported that they would consider taking PrEP. Those who had taken PrEP were older and had higher educational attainment. Conclusions: The gap between the willingness to use PrEP and its uptake may be attributed to the cost of PrEP and issues of anonymity at healthcare settings in Singapore. National financing schemes are needed to expand access to PrEP if it is to make a meaningful effect to the Singapore HIV/AIDS response.

Additional keywords: HIV, HIV prevention, primary prevention.


References

[1]  Beyrer C, Baral SD, van Griensven F, Goodreau SM, Chariyalertsak S, Wirtz AL, Brookmeyer R. Global epidemiology of HIV infection in men who have sex with men. Lancet 2012; 380 367–77.
Global epidemiology of HIV infection in men who have sex with men.Crossref | GoogleScholarGoogle Scholar |

[2]  Molina JM, Capitant C, Spire B, Pialoux G, Cotte L, Charreau I, Tremblay C, Le Gall JM, Cua E, Pasquet A, Raffi F, Pintado C, Chidiac C, Chas J, Charbonneau P, Delaugerre C, Suzan-Monti M, Loze B, Fonsart J, Peytavin G, Cheret A, Timsit J, Girard G, Lorente N, Preau M, Rooney JF, Wainberg MA, Thompson D, Rozenbaum W, Dore V, Marchand L, Simon MC, Etien N, Aboulker JP, Meyer L, Delfraissy JF, Anrs Ipergay Study Group On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. N Engl J Med 2015; 373 2237–46.
On-demand preexposure prophylaxis in men at high risk for HIV-1 infection.Crossref | GoogleScholarGoogle Scholar |

[3]  Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, Goicochea P, Casapia M, Guanira-Carranza JV, Ramirez-Cardich ME, Montoya-Herrera O, Fernandez T, Veloso VG, Buchbinder SP, Chariyalertsak S, Schechter M, Bekker LG, Mayer KH, Kallas EG, Amico KR, Mulligan K, Bushman LR, Hance RJ, Ganoza C, Defechereux P, Postle B, Wang F, McConnell JJ, Zheng JH, Lee J, Rooney JF, Jaffe HS, Martinez AI, Burns DN, Glidden DV, iPrEx Study Team Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363 2587–99.
Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.Crossref | GoogleScholarGoogle Scholar |

[4]  Zablotska I, Grulich AE, Phanuphak N, Anand T, Janyam S, Poonkasetwattana M. PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers. J Int AIDS Soc 2016; 19 21119

[5]  Krakower D, Mayer KH. Engaging healthcare providers to implement HIV pre-exposure prophylaxis. Curr Opin HIV AIDS 2012; 7 593–9.
Engaging healthcare providers to implement HIV pre-exposure prophylaxis.Crossref | GoogleScholarGoogle Scholar |

[6]  Singapore Ministry of Health (MoH). Update on the HIV/AIDS situation in Singapore 2016 (June 2017). City: Publisher; 2017. Available online at: https://www.moh.gov.sg/content/moh_web/home/statistics/infectiousDiseasesStatistics/HIV_Stats/update-on-the-hiv-aids-situation-in-singapore-2016–june-2017-.html [verified 18 May 2018].

[7]  Chua LJSD, Tan RKJ, Jie KW. Decriminalisation of same-sex relations and social attitudes: an empirical study of Singapore. Hong Kong Law J 2017; 47 793–824.

[8]  Mathews M, Gee C, Chiang WF, World S. Singapore perspectives 2014: differences. Hackensack, N.J; Singapore; World Scientific Pub. Co; 2015.

[9]  Saad I. Why we should leave Section 377A alone: PM [Prime Minister]. The Straits Times, 23 October 2007.

[10]  Health Sciences Authority. Bringing personal medications into Singapore 2017. Singapore: Health Sciences Authority; 2018. Available online at: http://www.hsa.gov.sg/content/hsa/en/Health_Products_Regulation/Consumer_Information/Personal_Import_Regulations/bringing_personal_medication_into_Singapore.html [verified 20 May 2018].

[11]  Teo J. New drug to prevent HIV infections available here. Singapore: Singapore Press Holdings; 2016. Available online at: http://www.straitstimes.com/singapore/health/new-drug-to-prevent-hiv-infections-available-here [verified 20 May 2018].

[12]  Tan KK. HIV pre-exposure prophylaxis – PrEP. Singapore: Dr Tan and Partners; 2014. Available online at: http://www.drtanandpartners.com/tablets-to-prevent-hiv-prep/ [verified 20 May 2018].

[13]  Singapore Government. Enlistment Act (Chapter 93); 1970. Available online at: https://sso.agc.gov.sg/Act/EA1970 [verified 20 May 2018].

[14]  Singapore Ministry of Manpower (MoM). Medical examination for foreign worker. Singapore: Ministry of Manpowwer; 2017. Available online at: http://www.mom.gov.sg/passes-and-permits/work-permit-for-foreign-worker/sector-specific-rules/medical-examination [verified 20 May 2018].

[15]  Singapore Government. Infectious Diseases Act (Chapter 137); 2003. Available online at: https://sso.agc.gov.sg/Act/IDA1976 [verified 20 May 2018].

[16]  Scanlin KK, Salcuni PM, Edelstein ZR, Daskalakis DC, Mensah NP, Tsoi B, Myers J. Increasing PrEP use among men who have sex with men, New York City, 2013–2015. Conference on Retroviruses and Opportunistic Infections (CROI); February 22–25 2016; Boston, MA, USA. San Francisco: CROI Foundation/IAS–USA; 2016.

[17]  Snowden JM, Chen Y-H, McFarland W, Raymond HF. Prevalence and characteristics of users of pre-exposure prophylaxis (PrEP) amongst men who have sex with men, San Francisco, 2014 in a cross-sectional survey: implications for disparities. Sex Transm Infect 2017; 93 52–5.
Prevalence and characteristics of users of pre-exposure prophylaxis (PrEP) amongst men who have sex with men, San Francisco, 2014 in a cross-sectional survey: implications for disparities.Crossref | GoogleScholarGoogle Scholar |

[18]  Hull P, Mao L, Lea T, Lee E, Kolstee J, Duck T, Feeney L, Prestage G, Zablotska I, de Wit J, Holt M. Gay community periodic survey: Sydney 2017. Sydney: Centre for Social Research in Health, UNSW Sydney; 2017.

[19]  Li R, Pan X, Ma Q, Wang H, He L, Jiang T, Wang D, Zhang Y, Zhang X, Xia S. Prevalence of prior HIV testing and associated factors among MSM in Zhejiang Province, China: a cross-sectional study. BMC Public Health 2016; 16 1152
Prevalence of prior HIV testing and associated factors among MSM in Zhejiang Province, China: a cross-sectional study.Crossref | GoogleScholarGoogle Scholar |

[20]  García M, Harris AL. PrEP awareness and decision-making for Latino MSM in San Antonio, Texas. PLoS One 2017; 12 e0184014
PrEP awareness and decision-making for Latino MSM in San Antonio, Texas.Crossref | GoogleScholarGoogle Scholar |

[21]  Guadamuz TE, Cheung DH, Wei C, Koe S, Lim SH. Young, online and in the dark: scaling up HIV testing among MSM in ASEAN. PLoS One 2015; 10 e0126658
Young, online and in the dark: scaling up HIV testing among MSM in ASEAN.Crossref | GoogleScholarGoogle Scholar |

[22]  Kahle EM, Sullivan S, Stephenson R. Functional knowledge of pre-exposure prophylaxis for HIV prevention among participants in a web-based survey of sexually active gay, bisexual, and other men who have sex with men: cross-sectional study. JMIR Public Health Surveill 2018; 4 e13
Functional knowledge of pre-exposure prophylaxis for HIV prevention among participants in a web-based survey of sexually active gay, bisexual, and other men who have sex with men: cross-sectional study.Crossref | GoogleScholarGoogle Scholar |

[23]  Chan RKW. Sections 377 and 377A of the Penal Code – Impact on AIDS Prevention and Control. The Act, issue 34; 2007.

[24]  Oogachaga. HIV Prevention in Singapore and MSM. Singapore: Oogachaga; 2011. Available online at: http://oogachaga.com/position1 [verified 20 May 2018].

[25]  Beyrer C, Sullivan PS, Sanchez J, Dowdy D, Altman D, Trapence G, Collins C, Katabira E, Kazatchkine M, Sidibe M, Mayer KH. A call to action for comprehensive HIV services for men who have sex with men. Lancet 2012; 380 424–38.
A call to action for comprehensive HIV services for men who have sex with men.Crossref | GoogleScholarGoogle Scholar |

[26]  Zou H, Fan S. Characteristics of men who have sex with men who use smartphone geosocial networking applications and implications for HIV interventions: a systematic review and meta-analysis. Arch Sex Behav 2017; 46 885–94.
Characteristics of men who have sex with men who use smartphone geosocial networking applications and implications for HIV interventions: a systematic review and meta-analysis.Crossref | GoogleScholarGoogle Scholar |

[27]  Singapore Government. Mobile Penetration Rate. Singapore: Info-communications Media Development Authority; 2018. Available online at: https://www.imda.gov.sg/industry-development/facts-and-figures/telecommunications#1x [verified 14 May 2018].