Articles citing this paper
The Multiple Properties of Gliotoxin and Other Epipolythiodioxopiperazine Metabolites
Paul Waring A D and Christina L. L. Chai B CA ANU College, Building 95, The Fulton Muir Building, The Australian National University, Canberra, ACT 0200, Australia.
B Institute of Chemical & Engineering Sciences, A*STAR (Agency for Science, Technology and Research), 8 Biomedical Grove, Neuros#07-01, Singapore 138665.
C Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543.
D Corresponding author. Email: Paul.Waring@anucollege.edu.au
![]() Paul Waring graduated with a B.Sc. (Hons) from the University of Queensland and gained a Ph.D. in 1978 under the supervision of Dr Des Brown. After a post-doctoral appointment in the Robert Robinson Laboratories in Liverpool, UK, Dr Waring returned to the John Curtin School of Medical Research (JCSMR) to study pteridine chemistry in Wilf Armarego's group. During this formative period, he developed an interest in both biochemistry and toxins. Following the discovery of the immunosuppressive effects of gliotoxin in the immunology department of the JCSMR, he was given an opportunity to apply chemical techniques to help unravel the mechanism of action of this unusual metabolite. This was followed by an involvement in the chemistry, biochemistry, and biology of gliotoxin over the next 20 years which extended into studies of apoptotic cell death induced by various toxins. He now teaches a Critical Thinking course at ANU College. |
![]() Christina Li Lin Chai obtained her B.Sc. (Hons) from the University of Canterbury, New Zealand, and her Ph.D. in synthetic organic chemistry from the Research School of Chemistry, ANU. She first joined the Chemistry Department at Victoria University of Wellington, New Zealand (1991–1993), then at ANU (1994–2004). The latter was where she met the late Professor Des Brown, mostly in the library while Des was doing his literature searches. Dr Chai moved to Singapore in December 2004, where she headed a research program in organic chemistry in the then newly founded Institute of Chemical and Engineering Sciences at the Agency for Science, Technology and Research (A*STAR). Since August 2011, Dr Chai has held a joint appointment as Associate Professor in the Department of Pharmacy, National University of Singapore, and in the Institute of Chemical and Engineering Sciences, A*STAR. Her research interests are in the areas of medicinal chemistry, green technologies, and synthesis of bioactive compounds and elucidation of their mechanisms. |
Australian Journal of Chemistry 68(2) 178-183 https://doi.org/10.1071/CH14482
Submitted: 1 August 2014 Accepted: 10 December 2014 Published: 23 January 2015