Articles citing this paper
Phenserine, a Novel Anticholinesterase Related to Physostigmine: Total Synthesis and Biological Properties
A Brossi, XF Pei and NH Greig
49(2) pp.171 - 181
38 articles found in Crossref database.
Total Synthesis of (±)-Phenserine via [4+1] Cyclization of a Bis(alkylthio)carbene and an Indole Isocyanate
Rigby James H., Sidique Shyama
Organic Letters. 2007 9(7). p.1219
Natural products: An evolving role in future drug discovery
Mishra Bhuwan B., Tiwari Vinod K.
European Journal of Medicinal Chemistry. 2011 46(10). p.4769
Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer’s disease
Martinez Ana, Castro Ana
Expert Opinion on Investigational Drugs. 2006 15(1). p.1
Alzheimer Disease (1997)
The Calabar Bean and its Alkaloids (2023)
Asymmetric Synthesis of Pyrrolidinoindolines. Application for the Practical Total Synthesis of (−)-Phenserine
Huang Audris,
Kodanko Jeremy J., Overman Larry E.
Journal of the American Chemical Society. 2004 126(43). p.14043
Blue Degradation Products of Rubreserine
Poobrasert Onoomar,
Cordell Geoffrey A., Bobzin Steven C.
Journal of Natural Products. 1997 60(6). p.578
Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development
Shaw Karen T. Y.,
Utsuki Tadanobu,
Rogers Jack,
Yu Qian-Sheng,
Sambamurti Kumar,
Brossi Arnold,
Ge Yuan-Wen,
Lahiri Debomoy K., Greig Nigel H.
Proceedings of the National Academy of Sciences. 2001 98(13). p.7605
Preparation of a new chiral building block containing a benzylic quaternary stereogenic center and a formal total synthesis of (−)-physostigmine
Asakawa Kaori,
Noguchi Naoyoshi,
Takashima Shingo, Nakada Masahisa
Tetrahedron: Asymmetry. 2008 19(19). p.2304
Synthesis of Novel Phenserine-Based-Selective Inhibitors of Butyrylcholinesterase for Alzheimer's Disease
Yu Qian-sheng,
Holloway Harold W.,
Utsuki Tadanobu,
Brossi Arnold, Greig Nigel H.
Journal of Medicinal Chemistry. 1999 42(10). p.1855
Indium(iii)-catalyzed intramolecular dearomative cycloaddition ofN-sulfonylaziridines to indoles: facile synthesis of tetracyclic pyrroloindoline skeletons
Cao Bo,
Wei Yin, Shi Min
Organic Chemistry Frontiers. 2018 5(3). p.423
The Calabar Bean and its Alkaloids (2023)
Syntheses and Anticholinesterase Activities of (3aS)-N,N8-Bisnorphenserine, (3aS)-N1,N8-Bisnorphysostigmine, Their Antipodal Isomers, and Other Potential Metabolites of Phenserine
Yu Qian-sheng,
Greig Nigel H.,
Holloway Harold W., Brossi Arnold
Journal of Medicinal Chemistry. 1998 41(13). p.2371
A Novel Synthetic Approach to (±)‐Desoxynoreseroline
Mekhael Maged K. G., Heimgartner Heinz
Helvetica Chimica Acta. 2003 86(8). p.2805
Natural products to drugs: natural product derived compounds in clinical trials
Butler Mark S.
Natural Product Reports. 2005 22(2). p.162
The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics
Greig N. H.,
De Micheli E.,
Holloway H. W.,
Yu Q.-S.,
Utsuki T.,
Perry T. A.,
Ingram D. K.,
Deutsch J.,
Lahiri D., Soncrant T. T.
Acta Neurologica Scandinavica. 2000 102 p.74
Drug Design and Discovery in Alzheimer's Disease (2014)
Cholinesterase inhibitors, β-amyloid precursor protein and amyloid β-peptides in Alzheimer's disease
Lahiri D. K.,
Farlow M. R.,
Hintz N.,
Utsuki T., Greig N. H.
Acta Neurologica Scandinavica. 2000 102 p.60
Natural products to drugs: natural product-derived compounds in clinical trials
Butler Mark S.
Natural Product Reports. 2008 25(3). p.475
Molybdenum‐Catalyzed Asymmetric Allylic Alkylation of 3‐Alkyloxindoles: Reaction Development and Applications
Trost Barry M., Zhang Yong
Chemistry – A European Journal. 2011 17(10). p.2916
Dearomative Indole Cycloaddition Reactions of Aza-Oxyallyl Cationic Intermediates: Modular Access to Pyrroloindolines
Acharya Arjun,
Anumandla Devendar, Jeffrey Christopher S.
Journal of the American Chemical Society. 2015 137(47). p.14858
Methyl Analogues of the Experimental Alzheimer Drug Phenserine: Synthesis and Structure/Activity Relationships for Acetyl- and Butyrylcholinesterase Inhibitory Action
Yu Qian-sheng,
Holloway Harold W.,
Flippen-Anderson Judith L.,
Hoffman Brian,
Brossi Arnold, Greig Nigel H.
Journal of Medicinal Chemistry. 2001 44(24). p.4062
Catalytic Asymmetric Synthesis of Either Enantiomer of the Calabar Alkaloids Physostigmine and Physovenine
Matsuura Takaharu,
Overman Larry E., Poon Daniel J.
Journal of the American Chemical Society. 1998 120(26). p.6500
Metal‐Free Synthesis of Oxazolidine‐2,4‐diones and 3,3‐Disubstituted Oxindoles via ICl‐Induced Cyclization
Yi Wei,
Fang Xing‐Xiao,
Liu Qing‐Yun, Liu Gong‐Qing
European Journal of Organic Chemistry. 2018 2018(47). p.6671
Conformational insights into furo‐ and thieno[2,3‐b]indolines derived from coupling constants and molecular modeling
Morales‐Ríos Martha S.,
Santos‐Sánchez Norma F.,
Pérez‐Rojas Nadia A., Joseph‐Nathan Pedro
Magnetic Resonance in Chemistry. 2004 42(11). p.973
A Formal Synthesis of (±)-Eseroline via an Azaoxy-Cope Rearrangement
M. Lobo Ana,
F. Santos Paulo,
S. Almeida Paulo, Prabhakar Sundaresan
HETEROCYCLES. 2001 55(6). p.1029
Palladium‐Catalyzed Enantioselective Domino Heck–Cyanation Sequence: Development and Application to the Total Synthesis of Esermethole and Physostigmine
Pinto Artur,
Jia Yanxing,
Neuville Luc, Zhu Jieping
Chemistry – A European Journal. 2007 13(3). p.961
Metal-free direct cyanoisopropylation/arylation of N-arylacrylamides or N-alkyl-N-(arylsulfonyl)acrylamides with AIBN: a simple and mild approach to cyano-containing oxindoles
Zhang Mingzhong,
Sheng Wenbing,
Ji Pengyi,
Liu Yufeng, Guo Cancheng
RSC Advances. 2015 5(70). p.56438
Synthesis of Isotope Labeled Me(3a)-13C-Physostigmine and Debromoflustramine B
S. Morales-Ríos Martha,
Joseph-Nathan Pedro,
F. Santos-Sánchez Norma, Mora-Pérez Yolanda
HETEROCYCLES. 2004 63(5). p.1131
The Calabar Bean and its Alkaloids (2023)
Synthesis of phenserine analogues and evaluation of their cholinesterase inhibitory activities
Shinada Masashi,
Narumi Fuminori,
Osada Yuji,
Matsumoto Koji,
Yoshida Takayasu,
Higuchi Kazuhiro,
Kawasaki Tomomi,
Tanaka Hiroyuki, Satoh Mitsutoshi
Bioorganic & Medicinal Chemistry. 2012 20(16). p.4901
Total Syntheses and Anticholinesterase Activities of (3aS)-N(8)-Norphysostigmine, (3aS)-N(8)-Norphenserine, Their Antipodal Isomers, and Other N(8)-Substituted Analogues
Yu Qian-sheng,
Pei Xue-Feng,
Holloway Harold W.,
Greig Nigel H., Brossi Arnold
Journal of Medicinal Chemistry. 1997 40(18). p.2895
Anticholinesterase Activity of Compounds Related to Geneserine Tautomers. N-Oxides and 1,2-Oxazines
Yu Qian-sheng,
Zhu Xiaoxiang,
Holloway Harold W.,
Whittaker Noel F.,
Brossi Arnold, Greig Nigel H.
Journal of Medicinal Chemistry. 2002 45(17). p.3684
Ab initio molecular structure study of alkyl substitute analogues of Alzheimer drug phenserine: structure–activity relationships for acetyl- and butyrylcholinesterase inhibitory action
Tezer Nurten
Journal of Molecular Structure: THEOCHEM. 2005 714(2-3). p.133
A formal synthesis of (±)-physostigmine via 3,3-rearrangement of a bis-enamine
Santos Paulo F.,
Srinivasan Natarajan,
Almeida Paulo S.,
Lobo Ana M., Prabhakar Sundaresan
Tetrahedron. 2005 61(38). p.9147
Synthesis of the AChE inhibitor [phenyl-7-3H] (−)-phenserine tartrate at high specific activity
Lacy J. M.,
Pounds S., Filer C. N.
Journal of Radioanalytical and Nuclear Chemistry. 2008 275(1). p.221
Structure, Bioactivity and Synthesis of Natural Products with Hexahydropyrrolo[2,3‐b]indole
Ruiz‐Sanchis Pau,
Savina Svetlana A.,
Albericio Fernando, Álvarez Mercedes
Chemistry – A European Journal. 2011 17(5). p.1388
ChemInform Abstract: Invited Review. Phenserine, a Novel Anticholinesterase Related to Physostigmine: Total Synthesis and Biological Properties
BROSSI A.,
PEI X.‐F., GREIG N. H.
ChemInform. 1996 27(33).
