Reproduction, Fertility and Development Reproduction, Fertility and Development Society
Vertebrate reproductive science and technology

Short Communication: Cloning of the red kangaroo (Macropus rufus) follicle stimulating hormone beta subunit

Katherine Belov, Gavan A. Harrison and Desmond W. Cooper

Reproduction, Fertility and Development 10(3) 289 - 292
Published: 1998


The cDNA encoding the follicle stimulating hormone beta subunit (FSH-β) was isolated from a red kangaroo pituitary cDNA library by using a porcine probe and the nucleotide sequence for the coding region was determined. The highest degree of deduced amino acid sequence identity (91%) was observed between the red kangaroo and another marsupial, the brushtail possum (Trichosurus vulpecula), followed by eutherian species (76%, 75% and 74%, respectively, for pig, mouse and sheep). Based on the deduced red kangaroo FSH-β amino acid sequence, putative antigenic sites have been identified that may prove useful for studying the hormonal control of reproduction in marsupials.

Keywords: marsupial, artificial breeding technology, conservation, immunocontraception.

© CSIRO 1998

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