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Vertebrate reproductive science and technology
RESEARCH ARTICLE

Detection of anti-ovarian antibodies by indirect immunofluorescence in patients with premature ovarian failure

R Kirsop, CR Brock, BG Robinson, RJ Baber, JV Wells and DM Saunders

Reproduction, Fertility and Development 3(5) 537 - 541
Published: 1991

Abstract

The sera of 30 patients with premature ovarian failure (POF) and a control group of 19 menopausal women were screened for anti-ovarian and other tissue antibodies. Anti-ovarian antibodies were detected by indirect immunofluorescence using monkey ovary substrates from two different commercial sources. Serum anti-ovarian antibodies were detected in only one of the patients with POF. This test does not appear to be reliable for the detection of serum anti-ovarian antibodies, and the clinical usefulness of screening patients with POF for anti-ovarian antibodies is questionable.

https://doi.org/10.1071/RD9910537

© CSIRO 1991

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