Editor-in-Chief - Tony Flint
Professor Tony Flint studied Biochemistry at St Andrew´s University (at Queen´s College, Dundee, which was then part of St Andrew´s), graduating in 1966. His first paper, published with David Stansfield in the Journal of Endocrinology in 1967, arose from his undergraduate research project on the active transport of ascorbate into luteal cells. This started a career involving the application of biochemical techniques to female reproductive physiology.
Professor Flint took his PhD in 1969 at Bristol, where he studied luteal glucose metabolism. He then spent 3 years in London, Ontario with David Armstrong, studying cholesterol ester metabolism in the corpus luteum. Returning to the UK in 1972 he worked on the initiation of labour in ruminants, with Alec Turnbull and Anne Anderson, firstly in Cardiff and then in Oxford. This work led to the discovery that the decrease in placental progesterone secretion at term was due to its conversion into oestrogen in the placenta, as a result of the induction of placental enzymes by fetal cortisol.
Moving to the BBSRC Institute at Babraham in 1977 Tony showed (with Linda Sheldrick, who was later to become his wife) that oxytocin stimulated uterine PGF2alpha production at luteolysis, and that this oxytocin was, unexpectedly, secreted by the corpus luteum itself. This led to the discovery (simultaneously with Mike Roberts in Florida) that interferon-tau is the maternal recognition of pregnancy signal in ruminants, and that it acts by down-regulating uterine oxytocin receptor expression.
In 1987 he was appointed to the Directorship of the Institute of Zoology in London, from where he moved to his present position as Professor of Animal Physiology at Nottingham University in 1993. He has published about 150 peer reviewed papers on a wide variety of species and has served on the editorial boards of a number of journals in reproductive biology.
Professor Tony Flint
Reproduction, Fertility and Development
School of Biosciences
University of Nottingham
Leicestershire LE12 5RD
Telephone +44 1159 516300
Telephone +61 3 9662 7629
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