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Article << Previous     |     Next >>   Contents Vol 26(1)

Molecular signatures of bovine embryo developmental competence

M. Hoelker A B, E. Held A, D. Salilew-Wondim A, K. Schellander A and D. Tesfaye A

A Institute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Endenicher Alle 15, 53115 Bonn, Germany.
B Corresponding author. Email: michael.hoelker@itz.uni-bonn.de

Reproduction, Fertility and Development 26(1) 22-36 http://dx.doi.org/10.1071/RD13255
Published: 5 December 2013


 
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Abstract

Assessment of the developmental capacity of early bovine embryos is still an obstacle. Therefore, the present paper reviews all current knowledge with respect to morphological criteria and environmental factors that affect embryo quality. The molecular signature of an oocyte or embryo is considered to reflect its quality and to predict its subsequent developmental capacity. Therefore, the primary aim of the present review is to provide an overview of reported correlations between molecular signatures and developmental competence. A secondary aim of this paper is to present some new strategies to enable concomitant evaluation of the molecular signatures of specific embryos and individual developmental capacity.

Additional keywords: embryo developmental competence, embryo quality, environment, gene expression, molecular signature.


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