Concerning the Proposed Structure of (+)-Laurobtusol: Spectral Discrepancies with Synthetic, Racemic Stereoisomers

Abstract

Laurobtusol, a minor metabolite from Laurencia obtusa, had been assigned constitution 1 and relative stereochemistry, 2. However, several stereoisomers of this novel, cyclopropane-containing system 1 have now been synthesized and spectral correspondence between the synthesized isomers and laurobtusol is lacking.