6,7,8,9-Tetrahydropyridoquinazolines, a new class of alkaloids from Mackinlaya species (Araliaceae)

Abstract

Leaves and stems of Mackinlaya subulata Philipson and M. macrosciadia (F. Muell.) F. Muell. (fam. Araliaceae) contain two new alkaloids, 6,7,8,9-tetra-hydropyrido[2,1-b]quinazolin-11-one (I), and 6,7,8,9-tetrahydro-llH-pyrido[2,1-b]- quinazoline (11), and the known alkaloid anabasine. The new Mackinlaya alkaloids had previously been prepared by synthesis^1-3.