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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

A total synthesis of indospicine, 6-Amidino-2-aminohexanoic acid

CCJ Culvenor, MC Foster and MPW Hegarty

Australian Journal of Chemistry 24(2) 371 - 375
Published: 1971

Abstract

Indospicine (1), the hepatotoxic amino acid from Indigofera spicata Forsk. is synthesized from 2-amino-6-hydroxyhexanoic acid (6- hydroxynorleucine) by stepwise replacement of hydroxyl by tosyloxy, cyano, imidoester, and amidine groupings.

https://doi.org/10.1071/CH9710371

© CSIRO 1971

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