Yb(OTf)3 –TMSCl, a Novel Catalytic System in Cross-Aldol Reactions
Natsuko Kagawa , Masahiro Toyota and
Masataka Ihara
Australian Journal of Chemistry
57(7) 655 - 657
Published: 07 July 2004
Abstract
A combination of Yb(OTf)3 and TMSCl influenced the outcome of cross-aldol reactions of cycloalkanones and benzaldehyde. Interestingly, reaction of cycloheptanone and cyclooctanone with aldehydes under the Yb(OTf)3–TMSCl reagent system provides 3-(2-oxocycloalkyl)-3-phenylpropanals in conjunction with the corresponding aldol products.https://doi.org/10.1071/CH04006
© CSIRO 2004
