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Open Access Article << Previous     |     Next >>   Contents Vol 52(9)

Effect of mycotoxin deactivator product supplementation on dairy cows

K. Kiyothong A E , P. Rowlinson B , M. Wanapat C and S. Khampa D

A Nakhonratchasima Animal Nutrition Research and Development Center, Nakhonratchasima 30130, Thailand.
B School of Agriculture, Food and Rural Development, University of Newcastle, Newcastle-upon-Tyne NE1 7RU, UK.
C Tropical Feed Resources Research and Development Center (TROFREC), Department of Animal Science, Faculty of Agriculture, Khon Kaen University, Khon Kaen 40002, Thailand.
D Faculty of Agricultural Technology, Rajabhat Maha Sarakham University, Maha Sarakham 44000, Thailand.
E Corresponding author. Email: kkiyothong@yahoo.co.uk

Animal Production Science 52(9) 832-841 http://dx.doi.org/10.1071/AN11205
Submitted: 27 September 2011  Accepted: 2 March 2012   Published: 3 July 2012


 
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Abstract

A total mixed ration (TMR) containing a blend of feedstuffs naturally contaminated with harmful mycotoxins was fed for 84 days to 24 primiparous and multiparous Holstein–Friesian × local dairy cows in a randomised complete block design. The dietary treatments consisted of a contaminated TMR diet plus various levels of the mycotoxin deactivator product (MDP) (0, 15, 30 or 45 g/head.day). Deoxynivalenol (DON), fumonisin B1 (FB1), zearalenone (ZON) and ochratoxin A (OTA) were found in the TMR at levels up to 720, 701, 541 and 501 μg/kg, whereas aflatoxin B1 (AfB1) and T-2 toxin (T-2) were found in the TMR at levels of 38 and 270 μg/kg, respectively. Rumen microbial ecology, ruminal volatile fatty acid (VFA) concentrations, ruminal microorganism populations, feed intake, total tract digestibility, milk yield, milk composition and serum immunoglobulin (Ig) concentrations were measured. The results revealed that the ruminal pH, ruminal ammonia nitrogen (NH3-N) concentration, total ruminal VFA concentrations and ruminal bacterial counts were significantly (P < 0.05) higher in supplemented than in non-supplemented cows. Ruminal protozoal counts were significantly (P < 0.05) lower in supplemented than in non-supplemented cows. DM intake, and digestibility of crude protein (CP) and neutral detergent fibre (NDF) were significantly (P < 0.05) higher in supplemented than in non-supplemented cows. Serum IgA concentrations were significantly (P < 0.05) higher in supplemented than in non-supplemented cows. Milk yield and milk protein were significantly (P < 0.05) higher in supplemented than in non-supplemented cows. On the basis of this experiment, it can be concluded that milk production and feed intake can be increased with the addition of MDP to cow diet in the presence of mycotoxins. These increases were accompanied by decreases in the negative effects of mycotoxins on rumen and immune function.

Additional keywords: digestibility, microorganism population, performance, rumen ecology, VFA concentration.


References

AOAC (1990) ‘Official methods of analysis.’ 15th edn. (Association of Official Analytical Chemists: Arlington, VA)

Beecher GR, Whitten BK (1970) Ammonia determination: reagents modification and interfering compounds. Analytical Biochemistry 36, 243–246.
CrossRef | CAS |

Bondy GS, Pestka JJ (2000) Immunomodulation by fungal toxins. Journal of Toxicology and Environmental Health, Part B 3, 109–143.
CrossRef | CAS |

CAST (2003) ‘Mycotoxins: risks in plant, animal, and human systems.’ Task Force Report 139. (Council for Agricultural Science and Technology: Ames, IA)

Charmley E, Trenholm HL, Thompson BK, Vudathala D, Nicolson JWG, Prelusky DB, Charmley LL (1993) Influence of level of deoxynivalenol in the diet of dairy cows on feed intake, milk production, and its composition. Journal of Dairy Science 76, 3580–3587.
CrossRef | CAS |

Cheng YH, Weng CF, Chen BJ, Chang MH (2006) Toxicity of different Fusarium mycotoxins on growth performance, immune responses and efficacy of a mycotoxin degrading enzyme in pigs. Animal Research 55, 579–590.
CrossRef | CAS |

Coulombe RA (1993) Symposium: biological action of mycotoxins. Journal of Dairy Science 76, 880–891.
CrossRef | CAS |

Dänicke S, Matthaus K, Lebzien P, Valenta H, Stemme K, Ueberschar KH, Razzazi-Fazeli E, Bohm J, Flachowsky G (2005) Effects of Fusarium toxin-contaminated wheat grain on nutrient turnover, microbial protein synthesis and metabolism of deoxynivalenol and zearalenone in the rumen of dairy cows. Journal of Animal Physiology and Animal Nutrition 89, 303–315.
CrossRef |

Diaz GJ, Cort’es A, Rold’an L (2005) Evaluation of the efficacy of four feed additives against the adverse effects of T-2 toxin in growing broiler chickens. Journal of Applied Poultry Research 14, 226–231.

Driehuis F, Spanjer MC, Scholten JM, Te Giffel MC (2008) Occurrence of mycotoxins in maize, grass and wheat silage for dairy cattle in the Netherlands. Food Additives and Contaminants 1, 41–50.
CrossRef | CAS |

Erdman RA, Proctor GH, Van Dersall JH (1986) Effect of rumen ammonia concentration on in situ rate and extent of digestion of feedstuffs. Journal of Dairy Science 69, 2312–2320.
CrossRef | CAS |

Ferguson J, Galligan D, Blanchard T, Reeves M (1993) Serum urea nitrogen and conception rate the usefulness of test information. Journal of Dairy Science 76, 3742–3746.
CrossRef | CAS |

Firkins JL (1996) Maximizing microbial protein-synthesis in the rumen. The Journal of Nutrition 126, 1347–1354.

Galyean M (1989) Laboratory procedure in animal nutrition research. Department of Animal and Life Science, New Mexico State University, Las Cruces, NM.

Gentry PA, Ross ML, Chan PKC (1984) Effect of T-2 toxin on bovine hematological and serum enzyme parameters. Veterinary and Human Toxicology 26, 24–28.

Goering H, Van Soest K (1970) ‘Forage fibre analysis. Agriculture hand book No.379.’ (United State Department of Agriculture: Washington, DC)

Hoover WH (1986) Chemical factors involved in ruminal fibre digestion. Journal of Dairy Science 69, 2755–2766.
CrossRef | CAS |

Hungate RE (1969) A roll tube method for cultivation of strict anaerobes. In ‘Methods in microbiology. Vol. 3B’. (Eds JR Norris, DW Ribbons) pp. 117–132. (Academic Press: London)

Jouany JP (1994) Manipulation of microbial activity in the rumen. Archives of Animal Nutrition 46, 133–153.

Korosteleva SN, Smith TK, Boermans HJ (2007) Effects of feedborne Fusarium mycotoxins on the performance, metabolism and immunity of dairy cows. Journal of Dairy Science 90, 3867–3873.
CrossRef | CAS |

Leng RA (1990) Forage utilisation by ruminants. Nutrition Research Reviews 3, 277–303.
CrossRef | CAS |

Lyle RR, Johnson RR, Wilhite JV, Backus WR (1981) Ruminal characteristics in steers as affected by adaptation from forage to all concentrate diets. Journal of Animal Science 53, 1383–1388.

Mancini GA, Carbonara O, Heremans JF (1965) Immunochemical quantification of antigens by single radial immunodifusion. Immunochemistry 2, 235–254.
CrossRef | CAS |

Mann DD, Buening MGM, Hook BS, Osweiler GD (1982) Effect of T-2 toxin on the bovine immune system: humoral factors. Infection and Immunity 36, 1249–1252.

Mertens DR (1977) Biological effects of mycotoxins upon rumen function in lactating dairy cows. In ‘Interactions of mycotoxins in animal production’. pp. 118–136. (National Academy Press: Washington, DC)

NRC (2001) ‘Nutrient requirements of dairy cattle.’ 7th edn. (National Academy Press: Washington, DC)

O’Brien CN, Guidry AJ, Douglass LW, Westhoff DC (2001) Immunization with Staphylococcus aureus Lysate incorporated into microspheres. Journal of Dairy Science 84, 1791–1799.
CrossRef | CAS |

Pier AC (1992) Major biological consequences of aflatoxicosis in animal production. Journal of Animal Science 70, 3964–3970.

Pietri A, Bertuzzi T, Piva G, Binder EM, Schatzmayr D, Rodrigues I (2009) Aflatoxin transfer from naturally contaminated feed to milk of dairy cows and the efficacy of a mycotoxin deactivating product. International Journal of Dairy Science 4, 34–42.
CrossRef | CAS |

Politis I, Fegeros K, Nitsch S, Schatzmayr G, Kantas D (2005) Use of Trichosporon mycotoxinivorans to suppress the effects of ochratoxicosis on the immune system of broiler chicks. British Poultry Science 46, 58–65.
CrossRef | CAS |

Rode LM (2008) ‘Maintaining a healthy rumen – An overview.’ Available at http://www.wcds.afns.ualberta.ca/Proceedings/2000/Chapter10.htm [verified 5 August 2009].

Roseler DK, Ferguson JD, Sniffen CJ, Herrema J (1993) Dietary protein degradability effects on plasma and milk urea nitrogen and milk non-protein in Holstein cows. Journal of Dairy Science 76, 525
CrossRef | CAS |

Russell JB, Wilson DB (1996) Why are ruminal cellulolytic bacteria unable to digest cellulose at low pH? Journal of Dairy Science 79, 1503–1509.
CrossRef | CAS |

Samuel M, Sagathewan S, Thomas J, Methen G (1997) An HPLC method for estimation of volatile fatty acid of ruminal fluid. Journal of Animal Science 67, 805–807.

SAS Institute Inc. (1989) ‘SAS/STAT user’s guide: version 6.’ 4th edn. (SAS Institute Inc.: Cary, NC)

Schatzmayr G, Zehner F, Schatzmayr D, Töaubel M, Binder EM (2006) Microbiologicals for deactivating mycotoxins in contaminated feed. Molecular Nutrition & Food Research 50, 543–551.
CrossRef | CAS |

Spahr U, Walther B, Sieber R, Gafner JL, Guidon D (1999) Occurrence of mycotoxins in feeds and carries over into milk. A review. Mitteilungen Lebensmittel und Hygiene 90, 575–609.

Steel RGD, Torrie JH (1980) ‘Principles and procedures of statistics: a biometrical approach.’ 2nd edn. (McGraw-Hill Inc.: New York)

Trenholm HL, Thompson BK, Hartin KE, Greenhalgh R, McAlister AJ (1985) Ingestion of vomitoxin (deoxynivalenol) contaminated wheat by nonlactation dairy cows. Journal of Dairy Science 68, 1000–1005.
CrossRef | CAS |

Valadares RFD, Broderick GA, Valadares Filho SC, Clayton MK (1999) Effect of replacing alfalfa silage with high moisture corn on ruminal protein synthesis estimated from excretion of total purine derivatives. Journal of Dairy Science 82, 2686–2696.

Van Keulen J, Young BA (1977) Evalution of acid insoluble ash as natural marker in ruminant digestibility studies. Journal of Animal Science 44, 282–287.

Vekiru E, Fruhauf S, Sahin M, Ottner F, Schatzmayr G, Krska R (2007) Investigation of various adsorbents for their ability to bind aflatoxin B1. Mycotoxin Research 23, 27–33.
CrossRef | CAS |

Whitlow LW, Hagler WM, Jr (2005) Mycotoxins: a review of dairy concerns. Available at https://www.sdstate.edu/vs/../Whitlow-Mycotoxins-MSRNC-2005.pdf [verified 1 June 2012]

Whitlow LW, Hagler WM, Jr (2008) ‘Mold and mycotoxin issues in dairy cattle: effects, prevention and treatment.’ Available at http://www.extension.org/pages/Mold_and_Mycotoxin_Issues_in_Dairy_Cattle:_Effects,_Prevention_and_Treatment [verified 1 August 2009]

Whitlow LW, Nebel RL, Hagler WM, Jr (1994) The association of deoxynivalenol in grain with milk production loss in dairy cows. In ‘Biodeterioration research 4: mycotoxins, wood decay, plant stress, biocorrosion, and general biodeterioration’. (Eds GC Liewellyn, WV Dashek, CE O’Rear) pp. 131–140. (Plenum Press: New York)

Woof JM, Kerr MA (2004) IgA function – variations on a theme. Immunology 113, 175–177.
CrossRef | CAS |


   
 


    
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