Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer-Supported Formate and Magnesium

Keelara Abiraj; Gejjalagere R. Srinivasa; D. Channe Gowda

doi:10.1071/CH04220

RESEARCH ARTICLE

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Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer-Supported Formate and Magnesium

Keelara Abiraj ^A , Gejjalagere R. Srinivasa ^A and D. Channe Gowda ^A ^B

+ Author Affiliations

- Author Affiliations

^A Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India.

^B Corresponding author. Email: dcgowda@yahoo.com

Australian Journal of Chemistry 58(2) 149-151 https://doi.org/10.1071/CH04220
Submitted: 18 September 2004 Accepted: 17 December 2004 Published: 21 February 2005

Abstract

Aromatic nitro compounds were chemoselectively reduced to the corresponding amines using recyclable polymer-supported formate as a hydrogen donor in the presence of low-cost magnesium powder at room temperature. Use of the immobilized hydrogen donor affords the product amine in excellent yield (90–97%) without the need for any chromatographic purification steps. This method was found to be highly facile with selectivity over several other functional groups, such as halogen, alkene, nitrile, carbonyl, ester, amide, methoxy, phenol, and hydroxyl groups.

Acknowledgments

We gratefully acknowledge financial support from the University Grants Commission, New Delhi. We also acknowledge the Council of Scientific and Industrial Research, New Delhi, for a research fellowship (to K.A.).

References

Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer-Supported Formate and Magnesium

Abstract

Acknowledgments

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