Australian Journal of Chemistry
Volume 70 Number 1 2017
Hydrogels have been gaining increasing popularity as biomimetic materials for their unique properties such as high water content, ease of functionalisation, and high biocompatibility. This highlight article describes the recent developments of hydrogels, with a large focus on the supramolecular variants, in their application for 3D cell cultures.
In this paper, we summarize recently reported breakthroughs in the arena of nanocatalysts for the oxidative coupling of thiols to their corresponding disulfides with the goal of stimulating further progress in this field.
This work presents a practical and simple alternative method for studying the leaching of copper from copper sulfide. It is demonstrated, for the first time, that micro-patterned thin films can be used as a model system for studying mineral leaching of copper-bearing minerals directly by measuring changes in the film thickness using white light interferometric profilometry and changes in the film morphology and elemental composition using scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy.
CH16126Direct Synthesis of Nitriles from Aldehydes and Hydroxylamine Hydrochloride Catalyzed by a HAP@AEPH2-SO3H Nanocatalyst
We describe an efficient method for the direct preparation of nitriles from aldehydes and hydroxylamine hydrochloride catalyzed by sulfonated nanohydroxyapatite functionalized by 2-aminoethyl dihydrogen phosphate (HAP@AEPH2-SO3H) as an eco-friendly and recyclable solid acid nanocatalyst.
CH16213Mo(CO)6 as a Solid CO Source in the Synthesis of Aryl/Heteroaryl Weinreb Amides under Microwave-Enhanced Condition
The facile transformation of aryl/heteroaryl nonaflates into corresponding amides via Pd-catalyzed aminocarbonylation using Mo(CO)6 as a solid CO source under microwave-enhanced condition is reported. The method was found to be tolerant with respect to a diverse range of electronically biased aryl/heteroaryl nonaflates, and exceptional yields were obtained. The optimized protocol was further extended to a diverse range of amines.
Amphiphilic peptides with or without oligoethylene glycol (OEG) chains based on 3,4-bis(benzyloxy)benzoic-linked glutamide were designed and their self-assembly was investigated. The studies showed that the amphiphilic peptide 3 with OEG chains could not only form stable gels in a wide range of solvents, but also allowed control of the width of nanofibres in the gel formed with changing water content.
CH16227The Importance of the Pauli Exchange-Type Repulsions and Hyperconjugative Interactions on the Conformational Properties of Halocarbonyl Isocyanates and Halocarbonyl Azides
The generalized anomeric relationships in halocarbonyl isocyanates (1–3) and halocarbonyl azides (4–6) result from the cooperative effects of the hyperconjugative generalized anomeric effects (HC-GAE) and Pauli exchange-type repulsion (PETR). The electrostatic model associated with the dipole–dipole interactions (EM-DDI) and the attractive electrostatic interactions (AEIs) between the natural atomic charges have no significant effects on the conformational preferences in compounds 1–3 and 4–6.
Ionic liquids are composed of ions only. However, they are not always completely soluble in water. Mixtures of phosphonium/phosphonate-type ionic liquids and water prepared herein exhibited stimuli-responsive phase transition, lower critical solution temperature phase transition, and thermoreversible viscosity change, and underwent rheopectic gelation depending on the water content
CH16321Organometallic Complexes for Non-Linear Optics. 59. Syntheses and Optical Properties of Some Octupolar (N-Heterocyclic Carbene)gold Complexes
The nonlinear optical (NLO) coefficients of (triphenylphosphine)gold alkynyl complexes are better than those of (N-heterocyclic carbene)gold alkynyl complexes; calculations suggest that the key low-energy transitions are from the (phosphine)gold to the alkynyl ligand in the former, and from the Au-alkynyl group to NHC in the latter.
CH16061Experimental and Quantum Mechanical Study of Nucleophilic Substitution Reactions of meta- and para-Substituted Benzyl Bromides with Benzylamine in Methanol: Synergy Between Experiment and Theory
This work involves the experimental and theoretical study of the nucleophilic substitution of meta- and para-substituted benzyl bromides with benzylamine.
CH16202Concerted Pathway to the Mechanism of the Anilinolysis of Bis(N,N-diethylamino)phosphinic Chloride in Acetonitrile
The kinetics of the nucleophilic substitution reactions of bis(N,N-diethylamino)phosphinic chloride with XC6H4NH2(D)2 are investigated in MeCN at 65.0°C. This study examines the substituent effects, deuterium kinetic isotope effects (DKIEs), and mechanism of the phosphoryl transfer reactions. A concerted SN2 mechanism involving the predominant backside attack is proposed.
This paper describes a simple way to synthesize poly(caprolactone) or poly(siloxane-block-caprolactone) copolymers through anionic polymerization by employing lithium silanolates.
CH16322Optimised Syntheses of the Half-Sandwich Complexes FeCl(dppe)Cp*, FeCl(dppe)Cp, RuCl(dppe)Cp*, and RuCl(dppe)Cp
Convenient, multigram scale syntheses of FeCl(dppe)Cp* (pictured), FeCl(dppe)Cp, RuCl(dppe)Cp*, and RuCl(dppe)Cp are described.
Al2O3 microspheres were prepared by cathode plasma electrolysis without additional heating treatment. The microspheres, with diameters of 5–30 μm, consisted of γ-Al2O3 and α-Al2O3. The mechanism and model were put forward in the formation process.
The peer-reviewed and edited version of record published online before inclusion in an issue
CH16566N-Heterocyclic Carbene-Catalysed Mukaiyama–Michael Reaction and Mukaiyama Aldol/Mukaiyama–Michael Three-Component Coupling Reaction
An N-heterocyclic carbene catalysed Mukaiyama–Michael addition between several TMS enol ethers and chalcone derivatives has been discovered. Also the related dehydrative Mukaiyama aldol followed by a Mukaiyama–Michael addition process has been developed. The enantioselective variant of these reactions has been examined with homochiral catalysts, which are active but fail to achieve enantioinduction.
CH16620Rage Against Conformity: Ruthenium(ɪɪ) Bisterpyridine Complexes Respond to Crystal Engineering Instructions with Whelming Results
Functionalised ruthenium(ii) bisterpyridine complexes refuse to obey crystal-engineering hydrogen-bond instructions.
CH16609Study on the Acid-Induced Ring-Expansion of an Oxaphosphirane Complex with an Electron-Withdrawing C-Substituent
A study on the acid-induced ring-expansion reaction of the first oxaphosphirane complex bearing C6F5 as an electron-withdrawing C-substituent using trifluoromethanesulfonic acid and electronically different aldehydes is described. The stereoselectively obtained 1,3,4-dioxaphospholane complexes 4a–c were unambiguously characterized by elemental analysis, multinuclear NMR, mass spectrometry, and single crystal X-ray diffraction studies.
Nickel–iron hydrogenases produce and consume hydrogen using elaborate electron and proton transport machinery. Although synthetic modelling of nickel–iron hydrogenases has developed rapidly, it has largely ignored aspects of substrate transfer. Reported here are nickel–iron mimics bearing redox-active ferrocenyl ligands, these trinuclear systems representing advanced models of the native enyzmes.
Racemic 4 melts above 350°C despite its low molar mass and absence of Pauling hydrogen bonding. X-Ray and Hirshfeld surface analyses reveal excellent complementarity between homochiral molecules of 4, and layers of opposite handedness are linked by the aza-1,3-peri hydrogen interaction. Weak intermolecular forces are discussed in context of the Lipinski ‘rule of 5’ solubility criteria.
CH16540Synthesis and Liquid Crystalline Properties of a New Homologous Series of 4,5-Disubstituted 2H-[1,2,3]-Triazoles via Azide-Chalcone Oxidative Cycloaddition Reaction
Homologous series of 4,5-disubstituted 2H-[1,2,3]-triazole derivatives were synthesized from chalcones and sodium azide via CuI-catalyzed oxidative cycloaddition reaction in order to characterize their liquid crystalline properties by polarizing optical microscopy and differential scanning calorimetry.
Arguably the most famous of all small molecule reactive intermediates is the hydroxyl radical. Methods to generate hydroxyl radicals from organic precursors are rare, with only one known example for the solution phase. Mass spectrometry is a key identifying technique is this area, and reported herein are new HO and DO radical precursors based on the trimethylammonium benzyl alcohol motif.
Is formate an energy source? We achieve formate electrooxidation in a practical and convenient way. The precursor of the oxidation is free HCOO– in fuel liquid rather than Pt-HCOOH. Formate is able to bypass the undesirable poisoning path to alternatively form carbon dioxide.
CH16543Polyanhydride Nanoparticles: Thiol–Ene ‘Click’ Polymerizations Provide Functionalized and Cross-Linkable Nanoparticles with Tuneable Degradation Times
Degradable polyanhydride-based nanoparticles are synthesized using thiol–ene ‘click’ polymerization followed by emulsification and solvent evaporation. These nanoparticles have tuneable degradation times, can be easily functionalized, and encapsulate payloads that can then be released upon degradation. Such degradable polymer nanoparticles have potential in many nano/bio-theranostic applications.
CH16580Brønsted Base-Mediated Aziridination of 2-Alkyl-Substituted-1,3-Dicarbonyl Compounds and 2-Acyl-Substituted-1,4-Dicarbonyl Compounds by Iminoiodanes
A Brønsted base-mediated method for the synthesis of α,α-diacylaziridines and α,α,β-triacylaziridines from reaction of 2-alkyl-substituted-1,3-dicarbonyl compounds and 2-acyl-substituted-1,4-dicarbonyl compounds with arylsulfonyliminoiodinanes (ArSO2N=IPh) under atmospheric conditions is described.
The emergence of antibiotic-resistant microbes and the lack of new antibiotics require development of new antimicrobial molecules and screening assays for them. We provide a proof of concept that a large unilamellar vesicle method used to study chloride ion efflux can be adapted to identify membrane-active antimicrobial peptides and screen their relative activity.
CH16587Syntheses, Structural Studies, and Copper Iodide Complexes of Macrocycles Derived from Williamson Ether Syntheses Involving 2,9-Bis(4-hydroxyphenyl)-1,10-phenanthroline, α,ω-Dibromides, and Resorcinol or 2,7-Dihydroxynaphthalene
The title macrocycles were assembled by first combining the grey and maroon building blocks, followed by a condensation with 1. The CuI moieties were markedly removed from the 1,10-phenanthroline planes, as represented by the basketball above the basket rim, and voids in the crystals were analyzed in the context of rotaxane formation.
The proton conductivity of graphene oxide has been reduced by 25 % after three years of aging due to the decrease in oxygen content and interlayer distance.
The simple cyclic tetrapeptide cyclo-(1,4)-[Ala-Arg-Ala-homoGlu]-NH2 (3) is shown to adopt an unusual α-turn structure. The latter structure is not α-helical but can nucleate α-helicity when attached to the N-terminus of either model peptides or two biologically relevant peptides. This new N-terminal helix-capping macrocycle provides simple and rapid synthetic access to α-helical peptide structures.
CH16621Interaction of Triplet Excited States of Ketones with Nucleophilic Groups: (π,π*) and (n,π*) versus (σ*,π*) States. Substituent-Induced State Switching in Triplet Ketones
The presence of nucleophilic substituents neighbouring a ketone functional group switches the character of the lowest triplet excited states from (π,π*) or (n,π*) to (σ*,π*).
CH16455Ilimaquinone and 5-epi-Ilimaquinone: Beyond a Simple Diastereomeric Ratio, Biosynthetic Considerations from NMR-Based Analysis
Ilimaquinone is a biologically active sesquiterpene isolated from Dactylospongia sponges. An intriguing diastereomeric ratio is observed based on an impressive collection of samples. Biosynthetic and ecological considerations stem from this study.
Two Q-based supramolecular assemblies were prepared via different approaches, and these Q-based supramolecular assemblies possess porous features that suggest that Q[n]-based compounds could be used to manufacture molecular sieves and sensors and applied in absorption and separation technologies
CH16556Molecular Assemblies and Spin-Crossover Behaviour of Cobalt(ɪɪ) Complexes with Terpyridine Incorporating Different Nitrogen Positions in Pyridine Rings
Cobalt(ii) complexes with terpyridine-type ligands, [Co(n-pyterpy)2](ClO4)2 (n = 3 (1), 4 (2)), show different molecular assemblies depending on the nitrogen position in the pyridine substituent. The cooperativity estimated from the magnetic behaviour reflects their assembly nature.
CH16577Crystal Structure of a Heterometallic Luminophore: The RuII Complex of a Ferrocenyl-Terpyridine with a Flexible Linkage
Crystal structure determination on the mixed ligand complex [Ru(tpy)(L1)](ClO4)2 (tpy = 2,2′:6′,2″-terpyridine; L1 = 4′-(ferrocenylmethylaminomethylphenyl)terpyridine) shows the ferrocenyl group to be located as remotely as possible from the RuII centre. This may explain the fact that emission from the RuII centre is detectable even at room temperature in solution.
In this work, oxidative stress (OS) models of methanol in mice were successfully established. The experimental results clearly demonstrated that methanol could stimulate the production of hydroxyl radicals in the liver of mice to induce OS. Rhubarb and vitamin C were found to have a protective effect on the liver of mice under acute OS.
CH166011,2-Diaryl-1,2-disodioethanes: Versatile, Highly Reactive, and Tunable Synthetic Equivalents of Sodium Metal
1,2-Diaryl-1,2-disodioethanes are easily prepared, versatile, and tunable diorganometals finding application in 1,2-reductive eliminations as well as in the degradation of several persistent organic pollutants as homogeneous synthetic equivalents of a highly reactive form of Na metal. Further applications as dinucleophiles and bases are also described.
The fruit fly insulin-like peptide 2, DILP2, is one of seven closely related peptides that each act upon the same insulin-like receptor. It was successfully chemically assembled by regioselective disulfide bond formation within its two synthetic chains and shown to potently stimulate receptor phosphorylation and downstream signalling.
Fijimycin A is a cyclic depsipeptide that has been shown to possess activity against a range of pathogenic bacteria. This communication describes the total synthesis of norfijimycin A, a simplified analogue of the marine natural product fijimycin A. The natural product analogue was shown to possess significant activity against Mycobacterium tuberculosis, the etiological agent of tuberculosis.
Electric field effects on the kinetics and thermodynamics of radical reactions have a significant, non-directional component arising in the increased polarizability of resonance-stabilized species.
CH16584Structural Systematics for Lanthanide(III) Systems: Interactions of the Achiral Hexamminecobalt(III) Cation with Tris(dipicolinato)lanthanate(III) Anions
Structures of [Co(NH3)6][Ln(dipic)3] hydrates have been analysed in terms of the weak interactions occurring between the achiral cation and the chiral anions.
The introduction of an iterative ‘click’ step into solid phase peptide synthesis protocols provides a method for rapid functionalisation of peptide side chains with a range of diverse moieties.
CH16554Effective Dissolution of Biomass in Ionic Liquids by Irradiation of Non-Thermal Atmospheric Pressure Plasma
Lignocellulose has gained much interest as a potential renewable energy resource. However, it is hardly soluble. In this study, a non-thermal plasma was applied to dissolution of lignocellulose to ionic liquids. Chemically active species, which were generated by the plasma, induced decomposition of the lignin network, and consequently dissolution of biomass into ionic liquids was accelerated.
CH16510Molecular Insights into the Interaction Between the SPRY Domain-Containing SOCS Box Protein SPSB2 and Peptides Based on the Binding Motif from iNOS
Surface plasmon resonance and NMR spectroscopy were used to gain insights into the binding of iNOS-derived peptides to SPSB2. The complex interplay of peptide sequence and protein binding will inform efforts to design peptide therapeutics to disrupt the iNOS–SPSB interaction.
CH16537Dehydrogenative Coupling of Hydrosilanes and Alcohols by Alkali Metal Catalysts for Facile Synthesis of Silyl Ethers
The RO–H/H–Si cross-dehydrogenative coupling (CDC) of alcohols and hydrosilanes with high yield (up to 99 %) and chemoselectivity for the production of silyl ethers using alkali metal salts [MN(SiMe3)2] (M = Li, Na, K) as pre-catalysts and under ambient conditions is presented.
Cyclotides are a group of cysteine-rich peptides derived from plants. Their exceptional stability based on their head-to-tail cyclized backbone and cystine knot, together with their tolerance to sequence modifications, make them promising drug design scaffolds into which novel bioactive sequences may be grafted. These grafting applications are achievable by solid-phase peptide synthesis. This article describes recent developments in the chemical synthesis and enzyme-mediated cyclization of cyclotides.
In this paper, we introduce a novel aptasensor for fast detection of oxytetracycline (OTC), based on a triple helix molecular switch (THMS) complex formation. The limit of detection (LOD) of this sensor was 1.67 and 6.44 nM in phosphate buffer and milk samples, respectively. The sensor also showed a high selectivity towards OTC.
CH16547Synthesis and Structures of Rare Earth 3-(4?-Methylbenzoyl)-propanoate Complexes – New Corrosion Inhibitors
A series of rare earth (RE) 3-(4′-methylbenzoyl)propanoate (mbp–) complexes [RE(mbp)3(H2O)] (RE = Y, La, Ce, Nd, Ho, Er) have been prepared by either metathesis reactions between the corresponding rare earth chloride and Na(mbp) or protolysis of rare earth acetates by the free acid.
CH16224Open-Chain Crown-Ether-Derived Two-Photon Fluorescence Probe for Real-Time Dynamic Biopsy of Mercury Ions
The probe developed in the present study can selectively detect Hg2+ ions in live cells and living tissues without interference from other metal ions and the membrane-bound probes, and its quenching constant is 8.73 × 105 M–1.
CH16532Macrocyclic Peptidomimetics Prepared by Ring-Closing Metathesis and Azide–Alkyne Cycloaddition
Ring-closing metathesis (RCM) and copper(i)-catalyzed azide–alkyne cycloaddition (CuAAC) are powerful strategies to introducing a macrocycle. This review focusses on the current synthetic approaches to access biologically active macrocycles that target important therapeutic aims for conditions such as cancer, cataracts, HIV, and neurological diseases.
CH16357Ring-Opening Dispersion Polymerization of ʟ-Lactide with Polylactide Stabilizer in Supercritical Carbon Dioxide
The particle diameter distributions of PLLA show that the stabilizer S131 with short lipophilic segment could improve the particle diameter distribution range, compared with the long lipophilic segment of stabilizer S121. With increasing concentration of the stabilizer S131, the particle size decreased and particle distribution became narrow.
A stepwise conjugation technique was employed to synthesise a multiantigenic vaccine candidate against Group A streptococcus (GAS) through azide–alkyne cycloaddition and mercapto–maleimide reactions. The final vaccine candidate consists of four different components: two GAS antigens, a T-helper epitope, and the lipidic moiety dipalmitoyl serine (DPS).
CH16460Improved Extraction Yield of Citral from Lemon Myrtle Using a Cellulose-Dissolving Ionic Liquid
The extraction yield of citral from lemon myrtle using cellulose-dissolving ionic liquids was up to 2.1 times higher than that obtained using ethanol. The ionic liquid could be recycled and reused nine times for the extraction of citral.
CH16527Coordination Behaviour of 1-(4,2′:6′,4′′-terpyridin-4′-yl)ferrocene and 1-(3,2′:6′,3′′-terpyridin-4′-yl)ferrocene: Predictable and Unpredictable Assembly Algorithms
1-(4,2′:6′,4″-Terpyridin-4′-yl)ferrocene offers a fixed V-shaped N,N″-donor set, but this does not lead to a predictable assembly algorithm; polymer and metalloamacrocycle formations compete. Similar competitive behaviour is observed in coordination assemblies based on 1-(4,2′:6′,4″-terpyridin-4′-yl)ferrocene, with the greater conformational flexibility of the latter adding to the non-predictability of the assembly process.
As demonstrated in the recent literature, β-peptides can self-assemble into a range of materials. This highlight explores recent developments in the preparation of functional materials involving β-peptides, wherein the self-assembly of β-peptides is unperturbed by side chain functionalisation and leads to the formation of stable gels and scaffolds that can support cellular growth.
CH16392Synthesis and Characterisation of Hierarchically Porous HZSM-5 as Catalysts for the Synthesis of 2,3,5-Trimethyl-1,4-benzoquinone
Hierarchical HZSM-5 were synthesised by controlled desilication in alkaline medium and used as catalyst for the selective oxidation of 2,3,6-trimethylphenol to 2,3,5-trimethyl-1,4-benzoquinone. The combined studies suggested that the nature of the solvent, intrinsic acidity, and shape selectivity of the hierarchical structure ensured high catalytic properties.
An energetically viable pathway to the diterpene variediene is described. Only one of the three secondary carbocations along this pathway is predicted to be a minimum on the potential energy surface.
CH16499An Efficient Chemical Synthesis of Lassomycin Enabled by an On-Resin Lactamisation–Off-Resin Methanolysis Strategy and Preparation of Chemical Variants
Lasso peptides contain a unique 3-D topography (known as a lariat knot) and are touted as novel scaffolds for biomedical applications. The synthesis of the non-threaded lasso peptide lassomycin was accomplished by solid-phase peptide chemistry and a novel way to install the C-terminal ester on the fully unprotected peptide.
CH16347Synthesis and Evaluation of a Biocompatible Macromolecular Gadolinium Compound as a Liver-Specific Contrast Agent for MRI
Gadolinium complexes are widely applied as magnetic resonance imaging contrast agents. However, they have some undesirable properties, e.g. low relaxivity and target non-specificity. A new biocompatible macromolecular gadolinium compound has been synthesised as a liver-specific contrast agent. The ability to improve the imaging signal and the T1-relaxivity is satisfactory, and it has a long window imaging time with a low acute toxicity.
CH16488Cope Rearrangement in Bicyclo[5.1.0]octa-2,5-diene and its Mono- and Di-Hetero Analogues: A DFT Study
Cope rearrangement of bicycle[5.1.0]octa-2,5-diene and its 8-hetero- (N,O,P) and 4,8-dihetero-analogues has been investigated in the gas phase at the B3LYP/6-31+G* level. The results reveal that relative stabilities of the three-membered ring undergoing opening and the three-membered ring being formed as a result of the Cope rearrangement determine the feasibility and rate of the rearrangement.
CH16398A New Fluorometric Method for the Determination of Oxaliplatin Based on Cucurbituril Supramolecular Interaction
The fluorescence intensity of CB–PAL, CB–BER, or CB–COP system decreased with increasing amounts of oxaliplatin (l-OHP) added. The trend is attributed to the competition between l-OHP and PAL, BER, or COP molecules for occupancy of the CB cavity.
CH16406A Quantum Theory of Atoms-in-Molecules Perspective and DFT Study of Two Natural Products: Trans-Communic Acid and Imbricatolic Acid
Intramolecular H···H as well as C···H non-covalent interactions have been retrieved and characterized using quantum theory of atoms-in-molecules and the computed chemical reactivity index using HOMO–LUMO gap and molecular electrostatic potential surface have been compared with experimentally observed bioactivity parameter.
CH16288Preparation and Characterization of PA6-PEG/Li High Performance Static Dissipation Composites
A series of novel PA6-PEG/Li composites were developed by melt blending the PA6-PEG copolymer (10 wt-% PEG) with three different kinds of colourless lithium salts (LiCl, C18H35LiO2, LiAc). The PA6-PEG/LiCl composite showed an excellent static dissipation performance of 2.71 × 108 Ω square–1.
CH16407Synthesis of Multivalent [Lys8]-Oxytocin Dendrimers that Inhibit Visceral Nociceptive Responses
We demonstrate efficient ‘click’ synthesis of large dendrimeric oxidatively folded peptides with up to 16 copies of [Lys8]-oxytocin that maintain potency and structure.
The influence of organic backbone on the bonding modes of the dicarboxylates, conformations of the of the long and flexible dipyridyl ligand, and pore size in isoreticular metal–organic frameworks formed by three double pillared-layer CoII metal–organic frameworks with a pcu topology is discussed.
CH16364A Green and Convenient Route for the Regioselective Synthesis of New Substituted 3-Aryl-5H-indeno[1,2-c]pyridazines as Potential Monoamine Oxidase Type A Inhibitors
Several indeno[1,2-c]pyridazines were efficiently synthesised using the one-pot, three-component reaction of substituted indanones, arylglyoxalmonohydrates, and hydrazine in the presence of 1,5-diazabicyclo[4,3,0]non-5-ene (DBN) in water at room temperature.
CH16459Synthesis of a Tetraphenylethene-Substituted Tetrapyridinium Salt with Multifunctionality: Mechanochromism, Cancer Cell Imaging, and DNA Marking
A tetrapyridyl-substituted tetraphenylethylene (TPy-TPE) works as a good fluorescent visualiser for specific staining for cellular imaging and as a DNA marker.
CH16425Atomic Force Microscopy Studies of the Interaction of Antimicrobial Peptides with Bacterial Cells
Many antimicrobial peptides (AMPs) are membrane-active but their mode of action remains elusive. Most studies have been conducted with synthetic membrane systems but, more recently, atomic force microscopy has been utilized to reveal the effect of AMPs on bacterial cells and provide great insight into how this class of peptides lyse cells.
CH16454Effect of Hydrogen Peroxide on the Extraction of Components of Cedar Powder with Tetrabutylphosphonium Hydroxide Aqueous Solution at 60°C
Cedar powder was treated with ionic liquids and onium hydroxide aqueous solution under very mild condition such as at 60°C. Addition of hydrogen peroxide accelerated the dissolution of lignin fragments with larger molecular weights owing to scission of the lignin network structure.
CH16368Two 3D ZnII Metal–Organic Frameworks with 3- and 8-Fold Interpenetration: Syntheses, Structures, Photodegradation, and Photoluminescent Properties
Two novel zinc coordination polymers have been synthesised and characterised. Their topological structures show 4-connected 8- and 3-fold interpenetrating 3D frameworks. Furthermore, they exhibit good photodegradation capability and photoluminescence properties.
CH16138Effect of Alkyl Chain Length of Imidazolium Cation on the Electroreduction of CO2 to CO on Ag Electrode in Acetonitrile
Effect of imidazolium cation (MIM+) on the electroreduction of CO2 to CO was investigated by linear sweep voltammetry (LSV), cyclic voltammetry (CV), constant potential electrolysis (CPE), and density functional theory (DFT) computations. It is interesting to find that the catalytic effect of MIM+ is sensitive to the alkyl chain length on its N1-position.
Various glycosylation reactions were tried in an effort to synthesise β-linked tutin glycosides, found in toxic honeys. Cationic palladium-mediated glycosylation gave the α-linked tutin tetrabenzyl glucoside (5 : 1, α : β). Hydrogenolysis of the benzyl ether groups resulted in tutin double-bond migration. Epoxide opening and rearrangement were observed upon acetylation of the tutin glucoside.
A polyglycidyl methacrylate electrospun scaffold was fabricated encapsulating a lipophilic drug, PXS64. Efficacy of the developed scaffold was explored for skin scar therapy applications.
CH16333Syntheses and Characterizations of Three Organically Templated Zinc Phosphites with 12-Ring Channels
Three zinc phosphites have been synthesized and characterized. Their frameworks are constructed from 4-connected ZnO4 tetrahedra and 3-connected HPO3 pseudopyramids. There are 12-membered ring (12-MR) and 8-MR apertures in their (3,4)-connected network. Helical chains are observed in compound 3.
CoWO4/g-C3N4 was synthesized by precipitation and calcination, and used as a catalyst for oxidative desulfurization. In the process, CoWO4/g-C3N4 showed excellent desulfurization activity and the desulfurization rate reached 92.9 %. Moreover, the catalyst could be recycled at least five times without any clear decrease in catalytic activity.
CH16467Endocyclic and Endo–Exocyclic Silver(I) Complexes of Thiaoxaaza Macrocycles: Crystallographic and NMR Studies
Thiaoxaaza macrocycles incorporating NO2S2 (L1) and NO2S3 (L2) donors were employed and their silver(i) nitrate complexation in solid and solution states was investigated.
The construction of the first Salen-type 3D lanthanide complex using Salen ligands and mixed lanthanide counter-ions is described.
CH16236Novel SrO-CaO Mixed Metal Oxides Catalyst for Ultrasonic-Assisted Transesterification of Jatropha Oil into Biodiesel
Novel strontium oxide/calcium oxide (SrO-CaO) mixed metal oxides heterogeneous catalyst is synthesized to highlight its catalytic potential for the transformation of Jatropha oil to green biofuels via an ultrasonic-assisted transesterification process.
CH16180Synthesis of a Novel Dibenzylamide Derivative of p-tert-Octylcalixarene and its Extraction Properties Towards Noble Metal Ions
A N,N-dibenzylacetoamide derivative of p-tert-octylcalixarene has been synthesised and its solvent extraction of precious metals in nitric acid media was investigated for determining the effects of extractant concentration and its contact time as well as nitric acid concentration in comparison with a N,N-diethylacetoamide derivative.
CH16200Oxidative N-Dealkylation of Tertiary Amines with Tetraethylammonium Periodate Catalyzed by Metal Complexes
Oxidative N-dealkylation of tertiary amines with tetraethyl ammonium periodate led to formation of corresponding N-dealkylated and mono-oxygenated products. One electron transfer dominates over hydrogen abstraction in the reaction mechanism.
CH16165Computational Studies on the Encapsulation of 1,4-Dihydropyridine Derivatives into CNT(10,10)
This paper investigates the use of (10,10) armchair carbon nanotube (CNT(10,10)) as a new drug delivery system for 1,4-dihydropyridine derivatives.
CH16250Preparation of Magnetic Surface-Imprinted Polymer Microspheres with Hydrophilic External Layers for Selective Extraction of Fluoroquinolones from Eggs
Novel restricted access media–molecularly imprinted magnetic microspheres that displayed water-compatibility, exclusion of biomacromolecules, and selective enrichment of analytes were prepared by a one-pot surface imprinting method for the magnetic dispersion microextraction of trace fluoroquinolones from egg samples.
Although PhI(OAc)2 is known as an oxidizing agent, it can also serve as a reagent or a catalyst in different types of chemical reactions in organic synthesis. PhI(OAc)2 is used in radical reactions, oxidation reactions, and in heterocycle synthesis. This paper reports some relevant and recent new uses of PhI(OAc)2.
CH16344Preparation and UCST-Type Phase Behaviours of Poly(γ-4-methylbenzyl-
l-glutamate) Pyridinium Tetrafluoroborate Conjugates in Methanol or Water
Poly(γ-4-methylbenzyl-L-glutamate) pyridinium tetrafluoroborate conjugates with constant main chain length, various pyridinium pendants, and high grafting efficiency can be readily prepared by nucleophilic substitution and ion-exchange reaction. They can exhibit reversible UCST-type phase behaviours in both methanol and water depending on the type of pyridinium pendants.
These articles have been peer reviewed and accepted for publication. They are still in production and have not been edited, so may differ from the final published form.
A theoretical probe for structures, metal-metal bonding and electronic spectra of paramagnetic tetrapyrrolic Ru(II) complex
Syntheses and structure investigations of 3d transition metal complexes with a flexible N4O2-donor hexadentate Schiff-base ligand
A Novel Interpenetrating Meal-organic Framework: Synthesis, Structure and Luminescence Detection of Nitrobenzene
Luminescent functionalized supramolecular coordination polymers based on an aromatic carboxylic acid ligand for sensing of Hg2+ ion
In situ Spectroelectrochemical Investigations of Ru(II) Complexes with Bispyrazolyl Methane Triarylamine Ligands
Perspective view of Metal Organic Frameworks and other existing materials as a drug delivery carrier
Synthesis and characterization of Co1-xCuxFe2-xAlxO4 ferrite nano-scales as a potential candidate for high density data storage applications
The Most Read ranking is based on the number of downloads in the last 60 days from the CSIRO PUBLISHING website. Usage statistics are updated daily.
Synthesis of a Novel Diol-Functionalized Poly(ethylene glycol)-Bridged Dicationic Ionic Liquid and its Application in Copper-Catalyzed Amination of Aryl HalidesAustralian Journal of Chemistry 66 (5)Yinglei Wang, Jun Luo, Tianjiao Hou, Zuliang Liu
Australian Journal of Chemistry 67 (6)Drahomír Výprachtický, Dana Kaňková, Veronika Pokorná, Ivan Kmínek, Vagif Dzhabarov, Věra Cimrová
Australian Journal of Chemistry 8 (1)VA Garten, DE Weiss
A Simple and Efficient Two-Step Synthesis of 1,2,3-Triiodoarenes via Consecutive C–H Iodination/ipso-Iododecarboxylation Strategy: A Potential Application towards ortho-Diiodoarenes by Regioselective Metal–Iodine Exchange ReactionAustralian Journal of Chemistry 68 (6)Raed M. Al-Zoubi, Hussein Al-Mughaid, Robert McDonald
Synthesis, Photo-physical and Electrochemical Properties of Dendrimers with (S)-BINOL Core and Benzothiazole Surface UnitAustralian Journal of Chemistry 68 (1)Venkatesan Kalpana, Kannan Rajavelu, Perumal Rajakumar
The Application of the Schmidt Reaction and Beckmann Rearrangement to the Synthesis of Bicyclic Lactams: Some Mechanistic ConsiderationsAustralian Journal of Chemistry 63 (2)Ian T. Crosby, James K. Shin, Ben Capuano
A Mild and Convenient Synthesis of 1,2,3-Triiodoarenes via Consecutive Iodination/Diazotization/Iodination StrategyAustralian Journal of Chemistry 66 (12)Raed M. Al-Zoubi, Hassan Abul Futouh, Robert McDonald
Direct Synthesis of Nitriles from Aldehydes and Hydroxylamine Hydrochloride Catalyzed by a HAP@AEPH2-SO3H NanocatalystAustralian Journal of Chemistry 70 (1)Samane Memar Masjed, Batool Akhlaghinia, Monireh Zarghani, Nasrin Razavi
Australian Journal of Chemistry 69 (12)Kevin K. W. Kuan, Aylin M. C. Hirschvogel, Jonathan H. George
Australian Journal of Chemistry 61 (4)D. Alan R. Happer, Thomas Francis, Jonathan M. White
Effect of Modification Protocols on the Effectiveness of Gold Nanoparticles as Drug Delivery Vehicles for Killing of Breast Cancer CellsAustralian Journal of Chemistry 69 (12)Zahrah Alhalili, Daniela Figueroa, Martin R. Johnston, Joe Shapter, Barbara Sanderson
Trichloroisocyanuric Acid/Triphenylphosphine-Mediated Synthesis of Benzimidazoles, Benzoxazoles, and BenzothiazolesAustralian Journal of Chemistry 68 (1)Soodabeh Rezazadeh, Batool Akhlaghinia, Nasrin Razavi
A Simple and Economic Synthesis of Propargylamines by CuI-Catalyzed Three-Component Coupling Reaction with Succinic Acid as AdditiveAustralian Journal of Chemistry 62 (1)Gerui Ren, Jinli Zhang, Zheng Duan, Mengjun Cui, Yangjie Wu
Synthesis and SAR of a Library of Cell-Permeable Biotin-R8ERY* Peptidomimetics Inhibiting α4β7 Integrin Mediated Adhesion of TK-1 Cells to MAdCAM-1-FcAustralian Journal of Chemistry 65 (9)Stefanie Papst, Anaïs F. M. Noisier, Margaret A. Brimble, Yi Yang, Yih-Chih Chan, Geoffrey W. Krissansen
Efficient Synthesis of Novel Porphyrin Dimers with Versatile Linkers via Bis(dipyrromethanes) in an Excellent Mixed-SolventAustralian Journal of Chemistry 66 (8)Hongbin Zhao, Junxu Liao, Deliang Yang, Yujia Xie, Yongjun Xu, Hongke Wang, Bangying Wang
Australian Journal of Chemistry 56 (1)A. R. Ismail, Sidik bin Silong, Brian W. Skelton, Allan H. White
Australian Journal of Chemistry 56 (10)Annabel Wood, Michael Giersig, Michael Hilgendorff, Antonio Vilas-Campos, Luis M. Liz-Marzán, Paul Mulvaney
Facile Synthesis of Triarylmethanimine Promoted by a Lewis Acid–Base Pair: Theoretical and Experimental StudiesAustralian Journal of Chemistry 65 (10)Yan Liu, Qiwu Yang, Dongling Hao, Wenqin Zhang
Molecular Docking and Spectroscopic Study on the Interaction of Serum Albumin with Iron(III) Diamine SarcophagineAustralian Journal of Chemistry 68 (6)Bahman Vasheghani Farahani, Ghasem Rezanejade Bardajee, Farzaneh Hosseinpour Rajabi, Zari Hooshyar
Australian Journal of Chemistry 66 (8)Xi Liu, Yun-Zhi Yang, Chun-Hai Wang, Kun-Lin Huang