Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Recognition of a Flavin Analogue by Novel Bile Acid-Based Receptors: Effects of Hydrogen Bonding and Aromatic π-Stacking Interactions

Pradeep Kumar Muwal A , Rajesh Kumar Chhatra A , Shubhajit Das A and Pramod S. Pandey A B
+ Author Affiliations
- Author Affiliations

A Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.

B Corresponding author. Email: pramod@chemistry.iitd.ac.in

Australian Journal of Chemistry 70(12) 1263-1268 https://doi.org/10.1071/CH17220
Submitted: 22 April 2017  Accepted: 29 June 2017   Published: 28 July 2017

Abstract

Molecular recognition properties are reported for novel bile acid-based receptors that incorporate 2,6-diaminopyridine as a recognition unit. Apart from hydrogen-bonding interactions, the bile acid receptors exhibit significant aromatic π-stacking interactions with the aromatic fused ring of the flavin derivative. These studies provide rationalisation for the differences in binding behaviour of bile acid receptors having differing aromatic arm lengths towards a flavin analogue.


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