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An international journal for chemical science
EDITORIAL

Professor Edouard Nice

John D. Wade https://orcid.org/0000-0002-1352-6568 A * and Marie-Isabel Aguilar https://orcid.org/0000-0002-0234-4064 B *
+ Author Affiliations
- Author Affiliations

A Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic. 3010, Australia.

B Department of Biochemistry and Molecular Biology, Monash University, Clayton, Vic. 3800, Australia.




John D. Wade obtained his PhD in Biochemistry in 1980 at Monash University, Australia. He then received a Nuffield Foundation Fellowship to Cambridge, UK, at the MRC Laboratory of Molecular Biology working with R. C. Sheppard on modern methods of chemical peptide synthesis. In 1983, he returned to Australia to the Howard Florey Institute, the now Florey Institute of Neuroscience and Mental Health, University of Melbourne, where he has long headed the Laboratory of Peptide and Protein Chemistry. His interests are in chemical peptide synthesis of complex, functionalised peptides including antimicrobial peptides. Prof. Wade is a past NHMRC of Australia Principal Research Fellow and a Fellow of both the Royal Australian Chemical Institute and the Royal Society of Chemistry.



Prof. Marie-Isabel (Mibel) Aguilar is a Bioanalytical and Biophysical Chemist at Monash University whose research focuses on biomembrane nanotechnology, peptide biomaterials and peptidomimetic drug design. She completed her PhD in Chemistry at the University of Melbourne studying the metabolism and toxicity of paracetamol. She then completed a post-doctoral position at St Vincent’s Institute for Medical Research working on developing physical models for protein analysis and purification. She then moved to Monash University where her group focuses on peptide-based biomaterials, drug design and biomembrane nanotechnology and are developing novel compounds that allow us to exploit the potential of peptides as drugs and biomaterials.


Handling Editor: George Koutsantonis

Australian Journal of Chemistry 76(8) 311-317 https://doi.org/10.1071/CH23094
Submitted: 16 May 2023  Accepted: 17 May 2023   Published: 11 August 2023

© 2023 The Author(s) (or their employer(s)). Published by CSIRO Publishing.


References

[1]  C Hao, P Chen, H Zhang, S Setrerrahmane, H Xu, ‘Renovation of old drugs’ – can peptide drug conjugates lead the post-ADC era? Aust J Chem 2023, 76, 318.
         | ‘Renovation of old drugs’ – can peptide drug conjugates lead the post-ADC era?Crossref | GoogleScholarGoogle Scholar |

[2]  P Jin, L Li, EC Nice, C Huang, Nanomedicine-based modulation of redox status for cancer therapy. Aust J Chem 2023, 76, 337.
         | Nanomedicine-based modulation of redox status for cancer therapy.Crossref | GoogleScholarGoogle Scholar |

[3]  NC Smith, JM Matthews, DNA-binding, multivalent interactions and phase separation in transcriptional activation. Aust J Chem 2023, 76, 351.
         | DNA-binding, multivalent interactions and phase separation in transcriptional activation.Crossref | GoogleScholarGoogle Scholar |

[4]  TT Denton, AJL Cooper, Chemistry, biochemistry and clinical relevance of the glutamine metabolite α-ketoglutaramate/2-hydroxy-5-oxoproline. Aust J Chem 2023, 76, 361.
         | Chemistry, biochemistry and clinical relevance of the glutamine metabolite α-ketoglutaramate/2-hydroxy-5-oxoproline.Crossref | GoogleScholarGoogle Scholar |

[5]  C Browne, Gutenberg, chemistry and the advancement of knowledge. Aust J Chem 2023, 76, 372.
         | Gutenberg, chemistry and the advancement of knowledge.Crossref | GoogleScholarGoogle Scholar |

[6]  CL Hunter, J Bons, B Schilling, Perspectives and opinions from scientific leaders on the evolution of data-independent acquisition for quantitative proteomics and novel biological applications. Aust J Chem 2023, 76, 379.
         | Perspectives and opinions from scientific leaders on the evolution of data-independent acquisition for quantitative proteomics and novel biological applications.Crossref | GoogleScholarGoogle Scholar |

[7]  Z Huang, Y Tan, W Zhang, X Tang, EC Nice, C Huang, Hippo signaling in cancer: regulatory mechanisms and therapeutic strategies. Aust J Chem 2023, 76, 399.
         | Hippo signaling in cancer: regulatory mechanisms and therapeutic strategies.Crossref | GoogleScholarGoogle Scholar |

[8]  C Gregg, MJ Caine, Navigating natural product-related patents in Australia and beyond. Aust J Chem 2023, 76, 413.
         | Navigating natural product-related patents in Australia and beyond.Crossref | GoogleScholarGoogle Scholar |

[9]  RA Bradshaw, On the development of proteomics: a brief history. Aust J Chem 2023, 76, 418.
         | On the development of proteomics: a brief history.Crossref | GoogleScholarGoogle Scholar |

[10]  M Skwarczynski, G Zhao, V Ozberk, AK Giddam, ZG Khalil, M Pandey, WM Hussein, RJ Nevagi, MR Batzloff, RJ Capon, MF Good, I Toth, Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation. Aust J Chem 2023, 76, 429.
         | Polyphenylalanine as a self-adjuvanting delivery system for peptide-based vaccines: the role of peptide conformation.Crossref | GoogleScholarGoogle Scholar |

[11]  D Sun, R Chen, S Ma, Y Zhang, D Li, Implementation of network embedding strategy on proteome datasets from multi-source cancers to demonstrate marker proteins of cancers. Aust J Chem 2023, 76, 437.
         | Implementation of network embedding strategy on proteome datasets from multi-source cancers to demonstrate marker proteins of cancers.Crossref | GoogleScholarGoogle Scholar |

[12]  C Lucas-Valmalle, G Subra, P Verdié, M-L Kemel, V Daugé, K Puget, J Martinez, The C-terminal pentapeptide acein analogue (JMV3315) stimulates dopamine release in the brain. Aust J Chem 2023, 76, 448.
         | The C-terminal pentapeptide acein analogue (JMV3315) stimulates dopamine release in the brain.Crossref | GoogleScholarGoogle Scholar |

[13]  R Li, TNG Handley, W Li, NM O’Brien-Simpson, MA Hossain, JD Wade, Directed chemical dimerisation enhances the antibacterial activity of the antimicrobial peptide MSI-78(4–20). Aust J Chem 2023, 76, 455.
         | Directed chemical dimerisation enhances the antibacterial activity of the antimicrobial peptide MSI-78(4–20).Crossref | GoogleScholarGoogle Scholar |

[14]  D Zhang, L Dong, W Yang, K Wang, Identification of NQO1 as a target of herbal drug agrimol B in hepatocellular carcinoma. Aust J Chem 2023, 76, 465.
         | Identification of NQO1 as a target of herbal drug agrimol B in hepatocellular carcinoma.Crossref | GoogleScholarGoogle Scholar |

[15]  ESX Moh, A Zankl, NH Packer, Phenotyping CHST3 skeletal dysplasia from freezer-induced urine sediments. Aust J Chem 2023, 76, 476.
         | Phenotyping CHST3 skeletal dysplasia from freezer-induced urine sediments.Crossref | GoogleScholarGoogle Scholar |

[16]  T-H Lee, JW Checco, T Malcolm, CH Eller, RT Raines, SH Gellman, EF Lee, WD Fairlie, M-I Aguilar, Differential membrane binding of α/β-peptide foldamers: implications for cellular delivery and mitochondrial targeting. Aust J Chem 2023, 76, 482.
         | Differential membrane binding of α/β-peptide foldamers: implications for cellular delivery and mitochondrial targeting.Crossref | GoogleScholarGoogle Scholar |

[17]  B Ismail, S Jones, J Howl, A holistic approach towards a generalizable machine learning predictor of cell penetrating peptides. Aust J Chem 2023, 76, 493.
         | A holistic approach towards a generalizable machine learning predictor of cell penetrating peptides.Crossref | GoogleScholarGoogle Scholar |

[18]  JY Wang, W Zhang, MW Roehrl, VB Roehrl, MH Roehrl, An autoantigen profile from Jurkat T-Lymphoblasts provides a molecular guide for investigating autoimmune sequelae of COVID-19. Aust J Chem 2023, 76, 508.
         | An autoantigen profile from Jurkat T-Lymphoblasts provides a molecular guide for investigating autoimmune sequelae of COVID-19.Crossref | GoogleScholarGoogle Scholar |

[19]  JY Wang, W Zhang, VB Roehrl, MW Roehrl, MH Roehrl, An autoantigen-ome from HS-Sultan B-Lymphoblasts offers a molecular map for investigating autoimmune sequelae of COVID-19. Aust J Chem 2023, 76, 525.
         | An autoantigen-ome from HS-Sultan B-Lymphoblasts offers a molecular map for investigating autoimmune sequelae of COVID-19.Crossref | GoogleScholarGoogle Scholar |