Elaeocarpus alkaloids. II. (+)-Elaeocarpiline and (–)-isoelaeocarpiline, new indolizidine alkaloids from Elaeocarpus dolichostylis

Abstract

(+)-Elaeocarpiline and (-)-isoelaeocarpiline, two new alkaloids isolated from the leaves of Elaeocarpus dolichostylis Schltr., have been shown to be respectively (+)-15,16-dihydroelaeocarpine (III) and (-)-15,16-dihydroisoelaeocarpine (IV). The relative configuration has been assigned for all centres in (-)-isoelaeocarpiline, but the relative configuration at C 16 in (+)-elaeocarpiline remains uncertain.