The proton magnetic resonance spectra of N-nitroso derivatives of sarcosine, proline and iminodiacetic acid

Abstract

The proton magnetic resonance spectra of various N-nitroso derivatives of sarcosine, L-proline, and iminodiacetic acid, including some protected dipeptides, have been obtained. Magnetic non-equivalence and conformational isomerism arising from restricted rotation of the nitroso group are discussed in relation to the reported behaviour of other nitrosamines. Long-range shielding effects on protons at a considerable distance from the anisotropic nitrosamino centre were readily detected with these compounds.