Attempted Enantioselective Synthesis of Terbutaline. Unexpected Partial Racemization During Lithium Aluminum Hydride Reduction of a Secondary Amide
AC Donohue and WR Jackson
Australian Journal of Chemistry
48(10) 1741 - 1746
Published: 1995
Abstract
Syntheses leading to compounds related to the bronchodilator (–)- terbutaline via optically active cyanohydrins suffered unexpected partial racemization during lithium aluminium hydride reduction of key amide intermediates.
https://doi.org/10.1071/CH9951741
© CSIRO 1995
